LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 3 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 3. - Dataset (ID:20311)

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Cell Small Molecule Small Mol Concentration (uM) Time Point (hr) Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value Assay Plate Assay Well
MCF 10A-H2B-mCherry
0
95.66 27.76 10985 6712 1.6365 1.1284
MN20160318_Q01
H09
MCF 10A-H2B-mCherry Vorinostat
0.031667
95.66 27.76 2558 6712 0.3811 0.7706
MN20160318_Q01
L04
MCF 10A-H2B-mCherry
0
95.66 27.76 11260 6712 1.6774 1.1350
MN20160318_Q01
H09
MCF 10A-H2B-mCherry Trametinib
0.0016667
95.66 27.76 4518 6712 0.6731 0.9025
MN20160318_Q01
C03
MCF 10A-H2B-mCherry Alpelisib
0.01
95.66 27.76 13464 6712 2.0058 1.1838
MN20160318_Q01
H19
MCF 10A-H2B-mCherry Trametinib
0.01
95.66 27.76 3848 6712 0.5733 0.8643
MN20160318_Q01
M14
MCF 10A-H2B-mCherry Alpelisib
1.7783
95.66 27.76 10831 6712 1.6135 1.1246
MN20160318_Q01
G17
MCF 10A-H2B-mCherry Trametinib
0.00033333
95.66 27.76 1 6712 0.0001 -0.3428
MN20160318_Q01
K07
MCF 10A-H2B-mCherry
0
95.66 27.76 506 6712 0.0754 0.4429
MN20160318_Q01
F18
MCF 10A-H2B-mCherry Trametinib
0.01
95.66 27.76 2008 6712 0.2991 0.7173
MN20160318_Q01
M14
MCF 10A-H2B-mCherry Alpelisib
1.7783
95.66 27.76 1554 6712 0.2315 0.6626
MN20160318_Q01
G17
MCF 10A-H2B-mCherry Trametinib
1
95.66 27.76 1 6712 0.0001 -0.3428
MN20160318_Q01
K06
MCF 10A-H2B-mCherry Alpelisib
1.7783
95.66 27.76 8491 6712 1.2649 1.0603
MN20160318_Q01
F10
MCF 10A-H2B-mCherry Vorinostat
0.31623
95.66 27.76 8864 6712 1.3205 1.0715
MN20160318_Q01
K08
MCF 10A-H2B-mCherry Alpelisib
0.0033333
95.66 27.76 519 6712 0.0773 0.4475
MN20160318_Q01
H18
MCF 10A-H2B-mCherry Trametinib
0.00033333
95.66 27.76 13294 6712 1.9804 1.1803
MN20160318_Q01
I12
MCF 10A-H2B-mCherry Dasatinib
0.018333
95.66 27.76 2582 6712 0.3847 0.7727
MN20160318_Q01
C22
MCF 10A-H2B-mCherry Vorinostat
1.7783
95.66 27.76 1436 6712 0.2139 0.6461
MN20160318_Q01
G03
MCF 10A-H2B-mCherry Alpelisib
1.7783
95.66 27.76 4094 6712 0.6099 0.8789
MN20160318_Q01
F10
MCF 10A-H2B-mCherry Vorinostat
1.7783
95.66 27.76 53 6712 0.0079 0.0851
MN20160318_Q01
G03
MCF 10A-H2B-mCherry
0
95.66 27.76 1035 6712 0.1542 0.5794
MN20160318_Q01
F17
MCF 10A-H2B-mCherry Trametinib
0.00033333
95.66 27.76 5468 6712 0.8146 0.9489
MN20160318_Q01
I12
MCF 10A-H2B-mCherry
0
95.66 27.76 12693 6712 1.8909 1.1676
MN20160318_Q01
F17
MCF 10A-H2B-mCherry Trametinib
0.017783
95.66 27.76 1822 6712 0.2714 0.6963
MN20160318_Q01
D08
MCF 10A-H2B-mCherry Dasatinib
0.17783
95.66 27.76 70 6712 0.0104 0.1239
MN20160318_Q01
E22