LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 9 of 9: Calculated dose-response metrics for biological replicate 3 - Dataset (ID:20286)

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Cell Small Molecule GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC GR r2
MCF 10A Trametinib 0.0026 0.0021 0.1170 0.1077 1.2989 0.6461 0.9968
MCF 10A Trametinib 0.0031 0.0028 0.0794 0.0633 1.3314 0.6520 0.9917
MCF 10A Taxol 0.0022 0.0028 -0.2271 -0.2020 1.4423 0.6300 0.9906
MCF 10A-H2B-mCherry Taxol 0.0022 0.0028 -0.2604 -0.2256 1.5275 0.6469 0.9949
MCF 10A Taxol 0.0024 0.0031 -0.2858 -0.2644 1.5756 0.6493 0.9955
MCF 10A Taxol 0.0023 0.0031 -0.3165 -0.3042 1.6318 0.6752 0.9981
MCF 10A-H2B-mCherry Trametinib 0.0050 0.0037 0.1825 0.1771 1.5030 0.5440 0.9983
MCF 10A Trametinib 0.0047 0.0041 0.0903 0.0858 1.3718 0.5949 0.9980
MCF 10A Neratinib 0.0827 0.0877 -0.0628 -0.0389 1.2792 0.4175 0.9960
MCF 10A Neratinib 0.0875 0.0911 -0.0521 -0.0308 1.4915 0.4116 0.9975
MCF 10A Neratinib 0.1195 0.1285 -0.0528 -0.0545 1.4275 0.3770 0.9977
MCF 10A Palbociclib 0.1679 0.1316 0.0836 0.0727 0.6451 0.4443 0.9863
MCF 10A-H2B-mCherry Neratinib 0.1788 0.1640 0.0840 0.0624 1.5431 0.3101 0.9972
MCF 10A Dasatinib 0.1551 0.1892 -0.1852 -0.1185 1.0689 0.4887 0.9813
MCF 10A Dasatinib 0.1701 0.2304 -0.1347 -0.1314 0.7679 0.4692 0.9752
MCF 10A Etoposide 0.2705 0.2790 0.0077 -0.0217 1.3754 0.4012 0.9975
MCF 10A Etoposide 0.2907 0.3102 -0.0078 -0.0447 1.3173 0.4011 0.9962
MCF 10A Etoposide 0.3048 0.3297 -0.0213 -0.0568 1.3677 0.3947 0.9937
MCF 10A-H2B-mCherry Palbociclib 1.0510 0.3770 0.3397 0.4137 1.7134 0.2098 0.9434
MCF 10A-H2B-mCherry Etoposide 0.4090 0.4404 -0.0002 -0.0486 1.2536 0.3585 0.9975
MCF 10A Dasatinib 0.3035 0.4514 -0.0441 -0.1524 0.6704 0.4089 0.9722
MCF 10A Palbociclib 1.3506 0.5132 0.3027 0.3643 1.3476 0.2136 0.9368
MCF 10A Palbociclib 1.9907 0.6661 0.3558 0.3696 1.2277 0.1890 0.9675
MCF 10A-H2B-mCherry Dasatinib 0.5718 0.6948 0.0384 -0.0754 0.7208 0.3247 0.9802
MCF 10A Vorinostat 0.8751 0.9289 0.0055 -0.0446 1.4316 0.3161 0.9978
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