Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) - Dataset (ID:20276)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Number of Cells Primary Antibody (488) Secondary Antibody (488) Protein Detected (488) Mean Fluorescence Intensity (488) Primary Antibody (647) Secondary Antibody (647) Protein Detected (647) Mean Fluorescence Intensity (647) Plate Name Plate Well
A-375 Vemurafenib (-)-JQ1 1.0000 0.5333
uM
 48
hr
 2 3373 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 173.27 NGFR rabbit IgG(H+L) / donkey NGFR 195.44
A375-B1-rep2
D7
A-375 Vemurafenib GSK-J4 1.0000 0.5333
uM
 48
hr
 2 3446 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 193.35 NGFR rabbit IgG(H+L) / donkey NGFR 187.41
A375-B1-rep2
D6
COLO 858 Vemurafenib Garcinol 0.3160 0.5333
uM
 48
hr
 2 1674 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 281.10 NGFR rabbit IgG(H+L) / donkey NGFR 142.39
Colo858-B1-rep2
F3
COLO 858 Vemurafenib BIX-01294 0.3160 0.5333
uM
 48
hr
 2 1928 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 358.98 NGFR rabbit IgG(H+L) / donkey NGFR 120.70
Colo858-B1-rep2
F5
A-375 Vemurafenib AGK2 1.0000 0.5333
uM
 48
hr
 2 1946 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 233.50 NGFR rabbit IgG(H+L) / donkey NGFR 153.50
A375-B1-rep2
D5
A-375 Vemurafenib Entinostat 1.0000 0.5333
uM
 48
hr
 2 3686 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 391.97 NGFR rabbit IgG(H+L) / donkey NGFR 328.37
A375-B1-rep2
D4
COLO 858 Vemurafenib Epigallocatechin gallate 0.3160 0.5333
uM
 48
hr
 2 2802 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 324.58 NGFR rabbit IgG(H+L) / donkey NGFR 137.24
Colo858-B1-rep2
E8
A-375 Vemurafenib JW55 1.0000 0.5333
uM
 48
hr
 2 2687 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 161.93 NGFR rabbit IgG(H+L) / donkey NGFR 175.65
A375-B1-rep2
D3
A-375 Vemurafenib Vorinostat 1.0000 0.5333
uM
 48
hr
 2 2869 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 443.59 NGFR rabbit IgG(H+L) / donkey NGFR 119.80
A375-B1-rep2
D2
COLO 858 Vemurafenib I-BET 0.3160 0.5333
uM
 48
hr
 2 2224 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 161.45 NGFR rabbit IgG(H+L) / donkey NGFR 24.73
Colo858-B1-rep2
E7
COLO 858 Vemurafenib Decitabine 0.3160 0.5333
uM
 48
hr
 2 1367 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 214.98 NGFR rabbit IgG(H+L) / donkey NGFR 173.73
Colo858-B1-rep2
F2
COLO 858 Vemurafenib Methylstat 0.3160 0.5333
uM
 48
hr
 2 2202 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 242.84 NGFR rabbit IgG(H+L) / donkey NGFR 132.23
Colo858-B1-rep2
F6
COLO 858 Vemurafenib Ischemin 0.3160 0.5333
uM
 48
hr
 2 1246 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 336.98 NGFR rabbit IgG(H+L) / donkey NGFR 140.12
Colo858-B1-rep2
G7
A-375 Vemurafenib UNC1215 1.0000 0.5333
uM
 48
hr
 2 2762 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 166.53 NGFR rabbit IgG(H+L) / donkey NGFR 192.69
A375-B1-rep2
C8
A-375 Vemurafenib (+)-JQ1 1.0000 0.5333
uM
 48
hr
 2 2283 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 118.15 NGFR rabbit IgG(H+L) / donkey NGFR 74.90
A375-B1-rep2
C7
COLO 858 Vemurafenib C646 0.3160 0.5333
uM
 48
hr
 2 2126 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 248.60 NGFR rabbit IgG(H+L) / donkey NGFR 140.35
Colo858-B1-rep2
E3
A-375 Vemurafenib GSK-J2 1.0000 0.5333
uM
 48
hr
 2 3124 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 156.22 NGFR rabbit IgG(H+L) / donkey NGFR 175.54
A375-B1-rep2
C6
A-375 Vemurafenib Selisistat 1.0000 0.5333
uM
 48
hr
 2 2918 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 176.89 NGFR rabbit IgG(H+L) / donkey NGFR 184.29
A375-B1-rep2
C5
COLO 858 Vemurafenib Azacitidine 0.3160 0.5333
uM
 48
hr
 2 1199 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 281.80 NGFR rabbit IgG(H+L) / donkey NGFR 95.43
Colo858-B1-rep2
E2
COLO 858 Vemurafenib Mocetinostat 0.3160 0.5333
uM
 48
hr
 2 2847 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 153.05 NGFR rabbit IgG(H+L) / donkey NGFR 41.69
Colo858-B1-rep2
E4
A-375 Vemurafenib Belinostat 1.0000 0.5333
uM
 48
hr
 2 2075 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 151.98 NGFR rabbit IgG(H+L) / donkey NGFR 20.46
A375-B1-rep2
C4
A-375 Vemurafenib Rucaparib 1.0000 0.5333
uM
 48
hr
 2 2421 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 168.96 NGFR rabbit IgG(H+L) / donkey NGFR 176.80
A375-B1-rep2
C3
COLO 858 Vemurafenib (-)-JQ1 0.3160 0.5333
uM
 48
hr
 2 3387 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 288.83 NGFR rabbit IgG(H+L) / donkey NGFR 150.04
Colo858-B1-rep2
D7
A-375 Vemurafenib Veliparib 1.0000 0.5333
uM
 48
hr
 2 2518 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 186.55 NGFR rabbit IgG(H+L) / donkey NGFR 195.58
A375-B1-rep2
C2
A-375 Vemurafenib UNC669 1.0000 0.5333
uM
 48
hr
 2 2288 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 162.78 NGFR rabbit IgG(H+L) / donkey NGFR 184.93
A375-B1-rep2
B8