Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
COLO 858 Vemurafenib Trametinib Dasatinib 0.1000 0.0100 1.0000
uM
 72
hr
 2 683 654 0.0048 0.0066 0.9575 0.9516
COLO 858 Vemurafenib Trametinib Dasatinib 0.1000 0.0100 0.3160
uM
 72
hr
 3 1204 1175 0.0048 0.0045 0.9759 0.9731
COLO 858 Vemurafenib Trametinib Defactinib 3.1600 0.3160 0.3160
uM
 72
hr
 3 820 785 0.0049 0.0055 0.9573 0.9565
COLO 858 Vemurafenib Trametinib PF562271 3.1600 0.3160 3.1600
uM
 72
hr
 1 530 505 0.0049 0.0053 0.9528 0.9453
COLO 858 Vemurafenib Trametinib Dasatinib 0.1000 0.0100 0.3160
uM
 72
hr
 2 975 944 0.0051 0.0045 0.9682 0.9731
COLO 858 Vemurafenib Trametinib Dasatinib 3.1600 0.3160 1.0000
uM
 72
hr
 3 923 892 0.0051 0.0049 0.9664 0.9743
COLO 858 Vemurafenib Trametinib Dasatinib 0.3160 0.0316 0.3160
uM
 72
hr
 3 828 797 0.0051 0.0042 0.9626 0.9671
COLO 858 Vemurafenib Trametinib Dasatinib 1.0000 0.1000 1.0000
uM
 72
hr
 3 1006 974 0.0053 0.0044 0.9682 0.9751
COLO 858 Vemurafenib Trametinib Defactinib 3.1600 0.3160 0.3160
uM
 72
hr
 2 972 934 0.0053 0.0055 0.9609 0.9565
COLO 858 Vemurafenib Trametinib Saracatinib 3.1600 0.3160 3.1600
uM
 72
hr
 3 917 885 0.0054 0.0038 0.9651 0.9738
COLO 858 Vemurafenib Trametinib Saracatinib 1.0000 0.1000 3.1600
uM
 72
hr
 1 762 730 0.0054 0.0058 0.9580 0.9500
COLO 858 Vemurafenib Trametinib Saracatinib 3.1600 0.3160 0.3160
uM
 72
hr
 2 721 688 0.0055 0.0059 0.9542 0.9563
COLO 858 Vemurafenib Trametinib Saracatinib 3.1600 0.3160 0.3160
uM
 72
hr
 1 868 834 0.0057 0.0059 0.9608 0.9563
COLO 858 Vemurafenib Trametinib Dasatinib 0.3160 0.0316 3.1600
uM
 72
hr
 1 779 744 0.0058 0.0069 0.9551 0.9524
COLO 858 Vemurafenib Trametinib Saracatinib 1.0000 0.1000 3.1600
uM
 72
hr
 3 578 543 0.0059 0.0058 0.9394 0.9500
COLO 858 Vemurafenib Trametinib PF562271 0.3160 0.0316 3.1600
uM
 72
hr
 2 481 450 0.0060 0.0074 0.9356 0.9225
COLO 858 Vemurafenib Trametinib PF562271 1.0000 0.1000 3.1600
uM
 72
hr
 1 473 442 0.0060 0.0058 0.9345 0.9410
COLO 858 Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 3.1600
uM
 72
hr
 3 872 832 0.0060 0.0070 0.9541 0.9543
COLO 858 Vemurafenib Trametinib Saracatinib 1.0000 0.1000 3.1600
uM
 72
hr
 2 781 744 0.0062 0.0058 0.9526 0.9500
COLO 858 Vemurafenib Trametinib Defactinib 3.1600 0.3160 3.1600
uM
 72
hr
 3 643 599 0.0062 0.0069 0.9316 0.9329
COLO 858 Vemurafenib Trametinib Saracatinib 0.3160 0.0316 3.1600
uM
 72
hr
 2 830 793 0.0062 0.0072 0.9554 0.9542
COLO 858 Vemurafenib Trametinib Defactinib 3.1600 0.3160 0.3160
uM
 72
hr
 1 903 859 0.0062 0.0055 0.9513 0.9565
COLO 858 Vemurafenib Trametinib PF562271 3.1600 0.3160 1.0000
uM
 72
hr
 2 1075 1043 0.0062 0.0091 0.9702 0.9558
COLO 858 Vemurafenib Trametinib Dasatinib 1.0000 0.1000 3.1600
uM
 72
hr
 2 836 798 0.0063 0.0058 0.9545 0.9563
COLO 858 Vemurafenib Trametinib PF562271 3.1600 0.3160 3.1600
uM
 72
hr
 2 596 563 0.0064 0.0053 0.9446 0.9453