Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Trametinib JNK-IN-8 0.3160 0.0316 0.0000
uM
 72
hr
 3 631 237 0.3901 0.3640 0.3756 0.3926
MMAC-SF Vemurafenib Trametinib Defactinib 0.1000 0.0100 0.0000
uM
 72
hr
 3 717 237 0.4635 0.3602 0.3305 0.3691
MMAC-SF Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.0000
uM
 72
hr
 3 543 237 0.2895 0.2718 0.4365 0.4581
MMAC-SF Vemurafenib Trametinib Saracatinib 0.3160 0.0316 0.0000
uM
 72
hr
 1 551 237 0.3109 0.3736 0.4301 0.4306
MMAC-SF Vemurafenib Trametinib Defactinib 0.1000 0.0100 3.1600
uM
 72
hr
 2 374 238 0.1313 0.1329 0.6364 0.6191
MMAC-SF Vemurafenib Trametinib PF562271 0.3160 0.0316 0.3160
uM
 72
hr
 2 618 238 0.3285 0.3023 0.3851 0.3999
MMAC-SF Vemurafenib Trametinib Saracatinib 1.0000 0.1000 0.0000
uM
 72
hr
 1 509 238 0.2683 0.3271 0.4676 0.4508
MZ7-mel Vemurafenib Trametinib Dasatinib 1.0000 0.1000 1.0000
uM
 72
hr
 1 1151 238 0.2739 0.1798 0.2068 0.1885
MMAC-SF Vemurafenib Trametinib Defactinib 3.1600 0.3160 0.0000
uM
 72
hr
 3 577 239 0.3264 0.2955 0.4142 0.4057
MMAC-SF Vemurafenib Trametinib Dasatinib 1.0000 0.1000 0.0000
uM
 72
hr
 2 600 239 0.3415 0.3557 0.3983 0.4268
MMAC-SF Vemurafenib Trametinib Saracatinib 1.0000 0.1000 1.0000
uM
 72
hr
 1 655 239 0.4119 0.3026 0.3649 0.3593
MZ7-mel Vemurafenib Trametinib Dasatinib 0.1000 0.0100 0.3160
uM
 72
hr
 1 999 239 0.2280 0.2663 0.2392 0.2265
WM-115 Vemurafenib Trametinib Defactinib 0.0000 0.0000 1.0000
uM
 72
hr
 1 2779 239 0.6585 0.6483 0.0860 0.0808
MZ7-mel Vemurafenib Trametinib Defactinib 3.1600 0.3160 3.1600
uM
 72
hr
 1 815 239 0.1709 0.1687 0.2933 0.2871
A-375 Vemurafenib Trametinib I-BET151 0.1000 0.0100 0.0000
uM
 72
hr
 2 1880 239 0.1139 0.1100 0.1271 0.1113
MMAC-SF Vemurafenib Trametinib Dasatinib 3.1600 0.3160 0.0000
uM
 72
hr
 1 523 240 0.2677 0.2718 0.4589 0.4581
MMAC-SF Vemurafenib Trametinib Defactinib 0.1000 0.0100 0.0000
uM
 72
hr
 2 585 240 0.3331 0.3602 0.4103 0.3691
A-375 Vemurafenib Trametinib Defactinib 0.1000 0.0100 0.3160
uM
 72
hr
 1 1906 240 0.0943 0.0985 0.1259 0.1245
MZ7-mel Vemurafenib Trametinib PF562271 0.0000 0.0000 0.0000
uM
 72
hr
 3 4088 241 0.9460 1.0000 0.0590 0.0567
A-375 Vemurafenib Trametinib Defactinib 0.1000 0.0100 0.3160
uM
 72
hr
 2 2021 241 0.1007 0.0985 0.1192 0.1245
A-375 Vemurafenib Trametinib JNK-IN-8 0.3160 0.0316 0.0000
uM
 72
hr
 1 2404 241 0.1275 0.1366 0.1002 0.1053
MMAC-SF Vemurafenib Trametinib PF562271 0.1000 0.0100 0.3160
uM
 72
hr
 2 683 242 0.3813 0.3533 0.3543 0.3907
WM-115 Vemurafenib Trametinib Defactinib 0.0000 0.0000 1.0000
uM
 72
hr
 2 2729 242 0.6447 0.6483 0.0887 0.0808
MMAC-SF Vemurafenib Trametinib PF562271 0.3160 0.0316 0.0000
uM
 72
hr
 2 603 242 0.3121 0.3084 0.4013 0.3843
A-375 Vemurafenib Trametinib PF562271 0.3160 0.0316 3.1600
uM
 72
hr
 3 871 242 0.0316 0.0329 0.2778 0.2741