Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

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Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
COLO 858 Vemurafenib Trametinib Belinostat 3.1600 0.3160 0.0000
uM
 72
hr
 3 843 764 0.0171 0.0184 0.9063 0.8831
COLO 858 Vemurafenib Trametinib Belinostat 3.1600 0.3160 1.0000
uM
 72
hr
 1 716 498 0.0473 0.0457 0.6955 0.6841
COLO 858 Vemurafenib Trametinib Belinostat 3.1600 0.3160 1.0000
uM
 72
hr
 2 654 466 0.0408 0.0457 0.7125 0.6841
COLO 858 Vemurafenib Trametinib Belinostat 3.1600 0.3160 1.0000
uM
 72
hr
 3 635 409 0.0490 0.0457 0.6441 0.6841
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.0000
uM
 72
hr
 1 477 211 0.2634 0.2795 0.4423 0.4515
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.0000
uM
 72
hr
 2 547 258 0.2861 0.2795 0.4717 0.4515
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.0000
uM
 72
hr
 3 522 230 0.2891 0.2795 0.4406 0.4515
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.3160
uM
 72
hr
 1 389 120 0.2663 0.2574 0.3085 0.3200
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.3160
uM
 72
hr
 2 366 118 0.2455 0.2574 0.3224 0.3200
MMAC-SF Vemurafenib Trametinib JNK-IN-8 3.1600 0.3160 0.3160
uM
 72
hr
 3 392 129 0.2604 0.2574 0.3291 0.3200