Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset - HMS LINCS Database

Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

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Cell	Small Molecule 1	Small Molecule 2	Small Molecule 3	Small Mol 1 Concentration	Small Mol 2 Concentration	Small Mol 3 Concentration	Small Mol Conc Unit	Time Point	Time Point Unit	Replicate	Total Number of Cells (Nuclei)	Number of Apoptotic Cells	Relative Viability	Mean Relative Viability	Apoptosis Fraction	Mean Apoptosis Fraction
MMAC-SF	Vemurafenib	Trametinib	PF562271	3.1600	0.3160	1.0000	uM	72	hr	3	221	95	0.1089	0.1628	0.4299	0.4419
MMAC-SF	Vemurafenib	Trametinib	PF562271	3.1600	0.3160	3.1600	uM	72	hr	1	218	86	0.1141	0.1014	0.3945	0.4221
MMAC-SF	Vemurafenib	Trametinib	Defactinib	3.1600	0.3160	3.1600	uM	72	hr	2	218	79	0.1342	0.1361	0.3624	0.3969
MMAC-SF	Vemurafenib	Trametinib	PF562271	1.0000	0.1000	3.1600	uM	72	hr	3	206	96	0.0951	0.1236	0.4660	0.4924
MMAC-SF	Vemurafenib	Trametinib	PF562271	3.1600	0.3160	3.1600	uM	72	hr	2	203	82	0.1046	0.1014	0.4039	0.4221
MMAC-SF	Vemurafenib	Trametinib	PF562271	0.3160	0.0316	3.1600	uM	72	hr	3	203	100	0.0890	0.1329	0.4926	0.4906
MMAC-SF	Vemurafenib	Trametinib	Defactinib	3.1600	0.3160	3.1600	uM	72	hr	3	198	83	0.1110	0.1361	0.4192	0.3969
MMAC-SF	Vemurafenib	Trametinib	Defactinib	1.0000	0.1000	3.1600	uM	72	hr	3	195	113	0.0792	0.1361	0.5795	0.5198
MMAC-SF	Vemurafenib	Trametinib	PF562271	3.1600	0.3160	3.1600	uM	72	hr	3	186	87	0.0856	0.1014	0.4677	0.4221
MMAC-SF	Vemurafenib	Trametinib	PF562271	1.0000	0.1000	0.3160	uM	72	hr	2	158	157	0.0009	0.1712	0.9937	0.5833