Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of three compounds (viability/apoptosis dataset 2 of 2) - Dataset (ID:20273)

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Cell Small Molecule 1 Small Molecule 2 Small Molecule 3 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol 3 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 3.1600
uM
 72
hr
 2 1660 229 0.0719 0.0722 0.1380 0.1341
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 3.1600
uM
 72
hr
 1 1890 257 0.0821 0.0722 0.1360 0.1341
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 1.0000
uM
 72
hr
 3 10528 496 0.5041 0.5122 0.0471 0.0480
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 1.0000
uM
 72
hr
 2 10238 479 0.4904 0.5122 0.0468 0.0480
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 1.0000
uM
 72
hr
 1 11357 569 0.5421 0.5122 0.0501 0.0480
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 0.3160
uM
 72
hr
 3 20259 1054 0.9651 0.9140 0.0520 0.0504
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 0.3160
uM
 72
hr
 2 19593 1032 0.9327 0.9140 0.0527 0.0504
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 0.3160
uM
 72
hr
 1 17620 818 0.8443 0.9140 0.0464 0.0504
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 0.0000
uM
 72
hr
 3 19729 929 0.9447 1.0000 0.0471 0.0502
A-375 Vemurafenib Trametinib PF562271 0.0000 0.0000 0.0000
uM
 72
hr
 2 21851 1210 1.0372 1.0000 0.0554 0.0502