Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
A-375 Vemurafenib Saracatinib 1.000 0.000
uM
 72
hr
 1 3640 140 0.1832 0.1915 0.0385 0.0418
A-375 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 1 5187 137 0.3177 0.2831 0.0264 0.0325
COLO 858 Vemurafenib Dasatinib 0.100 0.316
uM
 72
hr
 1 1513 641 0.1246 0.1453 0.4237 0.3955
A-375 Vemurafenib Saracatinib 1.000 0.316
uM
 72
hr
 1 2328 167 0.1131 0.1190 0.0717 0.0733
A-375 Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 1 2168 298 0.0896 0.0889 0.1375 0.1262
COLO 858 Vemurafenib PF562271 1.000 0.000
uM
 72
hr
 1 1250 489 0.1372 0.1377 0.3912 0.4424
A-375 Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 1 1638 157 0.0775 0.0717 0.0958 0.0989
A-375 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 1 3804 246 0.2238 0.1826 0.0647 0.0764
COLO 858 Vemurafenib Dasatinib 0.100 3.160
uM
 72
hr
 1 1844 660 0.1691 0.1486 0.3579 0.3478
A-375 Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 1 1317 141 0.0616 0.0571 0.1071 0.0996
A-375 Vemurafenib Dasatinib 0.000 0.316
uM
 72
hr
 1 5949 318 0.2851 0.2714 0.0535 0.0654
COLO 858 Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 1 1347 812 0.0764 0.0748 0.6028 0.5989
A-375 Vemurafenib Saracatinib 3.160 0.000
uM
 72
hr
 1 3381 232 0.1648 0.1538 0.0686 0.0753
A-375 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 1 3770 78 0.2322 0.2659 0.0207 0.0217
COLO 858 Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 1 1252 898 0.0506 0.0508 0.7173 0.7144
A-375 Vemurafenib Saracatinib 3.160 0.316
uM
 72
hr
 1 2098 334 0.0923 0.0842 0.1592 0.1524
A-375 Vemurafenib Defactinib 0.100 0.000
uM
 72
hr
 1 13441 248 0.6323 0.4565 0.0185 0.0200
COLO 858 Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 1 1374 845 0.0756 0.0722 0.6150 0.5817
A-375 Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 1 1524 308 0.0637 0.0584 0.2021 0.2015
A-375 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 1 3156 117 0.1912 0.2100 0.0371 0.0374
COLO 858 Vemurafenib Dasatinib 1.000 0.316
uM
 72
hr
 1 840 724 0.0166 0.0153 0.8619 0.8976
A-375 Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 1 1136 225 0.0477 0.0453 0.1981 0.2134
A-375 Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 1 3774 124 0.1848 0.1953 0.0329 0.0349
WM-115 Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 1 1354 459 0.2327 0.2251 0.3390 0.3147
WM-115 Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 1 1476 418 0.2751 0.2647 0.2832 0.2681