Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 1 976 91 0.6778 0.5614 0.0932 0.0959
MZ7-mel Vemurafenib PF562271 0.100 3.160
uM
 72
hr
 2 1617 91 0.4402 0.4191 0.0563 0.0616
MMAC-SF Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 3 882 92 0.6051 0.5813 0.1043 0.1242
MMAC-SF Vemurafenib Dasatinib 3.160 3.160
uM
 72
hr
 2 471 92 0.2903 0.2918 0.1953 0.1993
A-375 Vemurafenib Dasatinib 0.100 1.000
uM
 72
hr
 2 2276 92 0.1106 0.1200 0.0404 0.0313
MZ7-mel Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 1 1177 92 0.3539 0.5276 0.0782 0.0734
A-375 Vemurafenib Dasatinib 0.100 0.316
uM
 72
hr
 2 3458 92 0.1704 0.1709 0.0266 0.0246
A-375 Vemurafenib PF562271 0.316 0.316
uM
 72
hr
 3 3852 93 0.2045 0.1991 0.0241 0.0233
A-375 Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 2 4327 93 0.2216 0.2010 0.0215 0.0218
MMAC-SF Vemurafenib JNK-IN-8 3.160 1.000
uM
 72
hr
 3 309 93 0.2121 0.3656 0.3010 0.2907
MMAC-SF Vemurafenib Defactinib 0.100 0.316
uM
 72
hr
 3 1311 94 0.7498 0.6679 0.0717 0.0750
MMAC-SF Vemurafenib Defactinib 0.100 0.316
uM
 72
hr
 2 1266 94 0.7221 0.6679 0.0742 0.0750
MZ7-mel Vemurafenib PF562271 0.316 1.000
uM
 72
hr
 1 2285 94 0.6321 0.4655 0.0411 0.0405
MZ7-mel Vemurafenib PF562271 1.000 3.160
uM
 72
hr
 2 1016 94 0.2660 0.2591 0.0925 0.0924
A-375 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 2 4429 94 0.2727 0.2659 0.0212 0.0217
MZ7-mel Vemurafenib PF562271 3.160 3.160
uM
 72
hr
 3 652 95 0.1607 0.1873 0.1457 0.1549
A-375 Vemurafenib Belinostat 0.100 0.000
uM
 72
hr
 3 6342 95 0.4770 0.4690 0.0150 0.0238
MZ7-mel Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 1 2405 95 0.7534 0.5199 0.0395 0.0507
MMAC-SF Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 3 345 95 0.1995 0.3311 0.2754 0.2885
MZ7-mel Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 1 1917 95 0.5943 0.7294 0.0496 0.0484
MZ7-mel Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 2 1259 96 0.3793 0.4386 0.0763 0.0724
MZ7-mel Vemurafenib PF562271 1.000 1.000
uM
 72
hr
 3 911 96 0.2351 0.3742 0.1054 0.0960
MZ7-mel Vemurafenib PF562271 0.316 0.000
uM
 72
hr
 1 1598 96 0.4333 0.5367 0.0601 0.0669
MZ7-mel Vemurafenib Defactinib 0.316 1.000
uM
 72
hr
 3 1331 96 0.2714 0.3676 0.0721 0.0695
MZ7-mel Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 2 1837 96 0.3501 0.3242 0.0523 0.0687