Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib PF562271 0.316 3.160
uM
 72
hr
 3 324 106 0.2207 0.2531 0.3272 0.3208
MMAC-SF Vemurafenib PF562271 3.160 0.316
uM
 72
hr
 3 319 126 0.1954 0.2184 0.3950 0.3304
MMAC-SF Vemurafenib JNK-IN-8 3.160 1.000
uM
 72
hr
 3 309 93 0.2121 0.3656 0.3010 0.2907
MMAC-SF Vemurafenib JNK-IN-8 3.160 0.316
uM
 72
hr
 2 296 50 0.2416 0.2619 0.1689 0.2293
MMAC-SF Vemurafenib PF562271 3.160 0.316
uM
 72
hr
 1 290 89 0.2035 0.2184 0.3069 0.3304
MMAC-SF Vemurafenib JNK-IN-8 3.160 3.160
uM
 72
hr
 3 285 67 0.2141 0.2478 0.2351 0.2217
MMAC-SF Vemurafenib PF562271 3.160 1.000
uM
 72
hr
 3 255 100 0.1569 0.2379 0.3922 0.3676
MMAC-SF Vemurafenib PF562271 3.160 3.160
uM
 72
hr
 1 250 98 0.1539 0.1255 0.3920 0.4181
MMAC-SF Vemurafenib PF562271 3.160 3.160
uM
 72
hr
 3 196 90 0.1073 0.1255 0.4592 0.4181
MMAC-SF Vemurafenib PF562271 3.160 3.160
uM
 72
hr
 2 191 77 0.1154 0.1255 0.4031 0.4181