Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
A-375 Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 2 6541 255 0.3291 0.3648 0.0390 0.0413
A-375 Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 3 6145 245 0.3089 0.3648 0.0399 0.0413
A-375 Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 1 9635 173 0.4953 0.4364 0.0180 0.0207
A-375 Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 2 8079 212 0.4118 0.4364 0.0262 0.0207
A-375 Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 3 7818 140 0.4019 0.4364 0.0179 0.0207
A-375 Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 1 5747 125 0.2943 0.3050 0.0218 0.0212
A-375 Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 2 6343 121 0.3257 0.3050 0.0191 0.0212
A-375 Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 3 5769 132 0.2951 0.3050 0.0229 0.0212
A-375 Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 1 4016 78 0.2061 0.2010 0.0194 0.0218
A-375 Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 2 4327 93 0.2216 0.2010 0.0215 0.0218
A-375 Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 3 3430 84 0.1752 0.2010 0.0245 0.0218
A-375 Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 1 3954 69 0.2034 0.1687 0.0175 0.0176
A-375 Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 2 3199 50 0.1648 0.1687 0.0156 0.0176
A-375 Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 3 2686 53 0.1378 0.1687 0.0197 0.0176
A-375 Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 1 4811 91 0.2471 0.2452 0.0189 0.0214
A-375 Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 2 4759 106 0.2436 0.2452 0.0223 0.0214
A-375 Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 3 4787 110 0.2448 0.2452 0.0230 0.0214
A-375 Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 1 3302 117 0.1667 0.1598 0.0354 0.0325
A-375 Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 2 3269 84 0.1667 0.1598 0.0257 0.0325
A-375 Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 3 2890 105 0.1458 0.1598 0.0363 0.0325
A-375 Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 1 2096 82 0.1054 0.1035 0.0391 0.0423
A-375 Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 2 2270 89 0.1142 0.1035 0.0392 0.0423
A-375 Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 3 1827 89 0.0910 0.1035 0.0487 0.0423
A-375 Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 1 1649 67 0.0828 0.0757 0.0406 0.0403
A-375 Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 2 1554 62 0.0781 0.0757 0.0399 0.0403