Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10136-2 | TPCA-1 | LSM-1136 |  | 9903786 | |
| 10274-1 | SB-3CT | LSM-4293 |  | 9883002 | |
| 10273-1 | Purvalanol A | LSM-3118 |  | 456214 | |
| 10262-1 | L-779450 | LSM-4283 |  | 9950176 | |
| 10271-2 | PD 98059 | LSM-3394 |  | 4713 | |
| 10270-1 | Oxamflatin | LSM-4290 |  | 4611 | |
| 10268-1 | Nutlin 3a | LSM-6351 |  | 11433190 | |
| 10228-2 | IKK16 | LSM-2309 |  | 9549298 | |
| 10267-1 | NU6102 | LSM-4287 |  | 4566 | |
| 10237-1 | 5-DFUR | 5-FdUR; Doxifluridine | LSM-6359 |  | 18343 |
| 10248-1 | Doxorubicin | Adriamycin | LSM-4062 |  | 31703 |
| 10283-1 | XRP44X | AG-G-87906 | LSM-4298 |  | 10339779 |
| 10272-1 | Pemetrexed | Alimta | LSM-6353 |  | 446556 |
| 10099-2 | Nilotinib | AMN-107 | LSM-1099 |  | 644241 |
| 10261-1 | Ixabepilone | Azaepothilone B; Ixempra | LSM-43293 |  | 216344 |
| 10056-2 | Selumetinib | AZD6244; Array142886 | LSM-1056 |  | 10127622 |
| 10508-1 | FTase Inhibitor I | B581 |  | 132887 | |
| 10008-3 | Sorafenib | BAY-439006 | LSM-1008 |  | 216239 |
| 10232-2 | Dactolisib | BEZ235; NVP-BEZ235 | LSM-4255 |  | 11977753 |
| 10133-2 | Afatinib | BIBW-2992 | LSM-43226 |  | 57519523 |
| 10258-1 | Ibandronate | Boniva | LSM-4279 |  | 44828485 |
| 10245-1 | Cisplatin | CDDP; cis-Diaminodichloroplatinum; Cisplatinum; Lederplatin; Briplatin; Cismaplat | LSM-4268 |  | |
| 10230-2 | Lestaurtinib | CEP-701 | LSM-1231 |  | 126565 |
| 10048 | PD184352 | CI-1040 | LSM-1048 |  | 6918454 |
| 10048-6 | PD184352 | CI-1040 | LSM-1048 | | 6918454 |