Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset (ID:20269)

Small Molecules Studied

HMS LINCS ID Name Alternative Names LINCS ID Structure Image PubChem CID
10035-2 Sigma A6730
KIN001-102; AKT inhibitor VIII; Akt1/2 kinase inhibitor
 LSM-1035 10196499
10062-3 GSK1070916
KIN001-216
 LSM-1062 46885626
10510-1 LY294002
LY-294002
 3973
10348-1 Z-Leu-Leu-Norvalinal
MG-115
 LSM-6358 9868928
10265-1 Pevonedistat
MLN 4924; MLN-4924; MLN4924
 LSM-6263 16720766
10281-1 Vinorelbine
Navelbine
 LSM-6302 5311497
10097-3 Erlotinib
OSI-774
 LSM-1097 176870
10102-3 Taxol
Paclitaxel
 LSM-1102 441276
10263-1 LBH589
Panobinostat
 LSM-4284 57519507
10243-1 CGC-11047
PG11047
 LSM-4266 476863
10345-3 Torkinib
PP242
 LSM-6357 57347681
10235-2 Everolimus
RAD001
 LSM-4258 53398658
10052-3 Sirolimus
Rapamycin
 LSM-1052 5040
10264-1 Methotrexate
Rheumatrex; Trexall; Amethopterin; MTX
 LSM-5690 126941
10517-1 Ro 32-0432
RO-320432
 127757
10260-1 Ispinesib
SB-715992
 LSM-5732 6851740
10189-2 Bosutinib
SKI-606
 LSM-1190 5328940
10282-1 Vorinostat
suberoylanilide hydroxamic acid (SAHA); Zolinza
 LSM-3828 5311
10175-3 Sunitinib
Sutent; SU11248
 LSM-42800 3086686
10236-1 17-AAG
Tanespimycin
 LSM-43239 151069
10247-1 Docetaxel
Taxotere
 LSM-6360 148124
10208-2 JNK-IN-5A
TCS JNK 5a; KIN001-188
 LSM-1209 766949
10507-1 Disulfiram
Tetraethylthiuram disulfide; TETD
 3117
10516-1 Ribavirin
Tribavirin
 37542
10223-2 AG1478
Tyrphostin
 LSM-1224 2051