Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
184B5	NM	Basal	17-AAG	HSP90	HSP90	0.8	uM	9095.037	0.1564	-0.6864	1.0013
600MPE	HR+	Luminal	17-AAG	HSP90	HSP90	0.16	uM	7791.05	0.6554	0.1738	0.7929
184A1	NM	Basal	17-AAG	HSP90	HSP90	4	uM	9047.037	0.4226	-0.6108	0.5262
184B5	NM	Basal	17-AAG	HSP90	HSP90	0.16	uM	9095.037	0.1746	-0.6499	1.0013
600MPE	HR+	Luminal	17-AAG	HSP90	HSP90	0.000256	uM	7791.05	0.9836	0.9588	0.7929
600MPE	HR+	Luminal	17-AAG	HSP90	HSP90	0.032	uM	7791.05	0.9305	0.8264	0.7929
184A1	NM	Basal	17-AAG	HSP90	HSP90	0.0064	uM	9047.037	0.9396	0.7765	0.5262
184A1	NM	Basal	17-AAG	HSP90	HSP90	0.8	uM	9047.037	0.4311	-0.5959	0.5262
184B5	NM	Basal	17-AAG	HSP90	HSP90	0.000256	uM	9095.037	1.0187	1.0373	1.0013
184B5	NM	Basal	17-AAG	HSP90	HSP90	0.032	uM	9095.037	0.4901	-0.0190	1.0013
184B5	NM	Basal	17-AAG	HSP90	HSP90	20	uM	9095.037	0.1104	-0.7785	1.0013
184B5	NM	Basal	17-AAG	HSP90	HSP90	100	uM	9095.037	0.0306	-0.9385	1.0013
600MPE	HR+	Luminal	17-AAG	HSP90	HSP90	0.00128	uM	7791.05	1.0197	1.0499	0.7929
600MPE	HR+	Luminal	17-AAG	HSP90	HSP90	0.0064	uM	7791.05	0.9733	0.9329	0.7929
184A1	NM	Basal	17-AAG	HSP90	HSP90	0.000256	uM	9047.037	0.9096	0.6705	0.5262
184A1	NM	Basal	17-AAG	HSP90	HSP90	0.00128	uM	9047.037	1.0758	1.2981	0.5262
184A1	NM	Basal	17-AAG	HSP90	HSP90	0.032	uM	9047.037	0.4452	-0.5704	0.5262
184A1	NM	Basal	17-AAG	HSP90	HSP90	0.16	uM	9047.037	0.4280	-0.6013	0.5262
184A1	NM	Basal	17-AAG	HSP90	HSP90	20	uM	9047.037	0.3683	-0.7003	0.5262
184A1	NM	Basal	17-AAG	HSP90	HSP90	100	uM	9047.037	0.0825	-0.9826	0.5262
184B5	NM	Basal	17-AAG	HSP90	HSP90	0.00128	uM	9095.037	1.0407	1.0812	1.0013
184B5	NM	Basal	17-AAG	HSP90	HSP90	0.0064	uM	9095.037	1.0285	1.0568	1.0013
184B5	NM	Basal	17-AAG	HSP90	HSP90	4	uM	9095.037	0.1154	-0.7686	1.0013
600MPE	HR+	Luminal	17-AAG	HSP90	HSP90	4	uM	7791.05	0.6195	0.0933	0.7929
600MPE	HR+	Luminal	17-AAG	HSP90	HSP90	0.8	uM	7791.05	0.6611	0.1867	0.7929

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)