Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
184B5	NM	Basal	Sigma A6730	AKT	AKT	0.107	uM	12566.165	0.9377	0.9268	1.7248
184B5	NM	Basal	Sigma A6730	AKT	AKT	0.0213	uM	12566.165	0.7594	0.7050	1.7248
184B5	NM	Basal	Sigma A6730	AKT	AKT	0.533	uM	12566.165	0.9043	0.8867	1.7248
600MPE	HR+	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	12224.165	0.9420	0.8806	0.9714
184B5	NM	Basal	Sigma A6730	AKT	AKT	0.000171	uM	12566.165	0.9288	0.9161	1.7248
184B5	NM	Basal	Sigma A6730	AKT	AKT	0.000853	uM	12566.165	0.9665	0.9609	1.7248
184B5	NM	Basal	Sigma A6730	AKT	AKT	0.00427	uM	12566.165	0.9614	0.9549	1.7248
600MPE	HR+	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	12224.165	0.9369	0.8701	0.9714
AU565	HER2amp	Luminal	Sigma A6730	AKT	AKT	66.7	uM	10880.153	0.0126	-0.8497	1.6896
BT-474	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.107	uM	12178.158	0.9985	0.9960	0.7379
CAMA-1	HR+	Luminal	Sigma A6730	AKT	AKT	0.533	uM	12070.158	0.9262	0.8683	1.1252
CAMA-1	HR+	Luminal	Sigma A6730	AKT	AKT	2.67	uM	12070.158	0.6919	0.4417	1.1252
CAMA-1	HR+	Luminal	Sigma A6730	AKT	AKT	13.3	uM	12070.158	0.3695	-0.1744	1.1252
184A1	NM	Basal	Sigma A6730	AKT	AKT	66.7	uM	12509.165	0.0713	-0.6553	1.5022
184A1	NM	Basal	Sigma A6730	AKT	AKT	13.3	uM	12509.165	0.4132	0.1106	1.5022
184A1	NM	Basal	Sigma A6730	AKT	AKT	2.67	uM	12509.165	0.6455	0.4945	1.5022
184A1	NM	Basal	Sigma A6730	AKT	AKT	0.533	uM	12509.165	0.8565	0.8041	1.5022
184A1	NM	Basal	Sigma A6730	AKT	AKT	0.107	uM	12509.165	0.9448	0.9258	1.5022
184A1	NM	Basal	Sigma A6730	AKT	AKT	0.0213	uM	12509.165	0.9735	0.9646	1.5022
184A1	NM	Basal	Sigma A6730	AKT	AKT	0.00427	uM	12509.165	1.0136	1.0181	1.5022
184A1	NM	Basal	Sigma A6730	AKT	AKT	0.000853	uM	12509.165	0.9938	0.9917	1.5022
184A1	NM	Basal	Sigma A6730	AKT	AKT	0.000171	uM	12509.165	0.9859	0.9812	1.5022
CAMA-1	HR+	Luminal	Sigma A6730	AKT	AKT	66.7	uM	12070.158	0.0394	-0.8870	1.1252
BT-474	HER2amp	Luminal	Triciribine	AKT	AKT	0.0533	uM	5906.074	0.7377	0.2472	0.6442
BT-474	HER2amp	Luminal	Triciribine	AKT	AKT	0.0107	uM	5906.074	0.7444	0.2648	0.6442

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)