Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Chloroquine | 0.00017 | uM | 12979.177 | 2.1512 | 6.7648 | 0.5647 | |||
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14176.189 | 1.9005 | 7.9498 | 0.4285 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14176.189 | 1.9005 | 7.9498 | 0.4285 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14176.189 | 1.9453 | 8.4502 | 0.4285 | |
| LY2 | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7477.066 | 1.7286 | 8.9593 | 0.3409 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7477.065 | 3.5926 | 9.1125 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7477.065 | 4.1296 | 11.0648 | 0.7891 |