Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21NT | HER2amp | - | Ribavirin | 0.08 | uM | 15383.211 | 1.0137 | 1.0265 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.016 | uM | 15383.211 | 0.9351 | 0.8743 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.4 | uM | 15383.211 | 1.0060 | 1.0116 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.00064 | uM | 15383.211 | 0.9100 | 0.8256 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.0032 | uM | 15383.211 | 0.9196 | 0.8443 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 2 | uM | 15383.211 | 1.0639 | 1.1234 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.000128 | uM | 15383.211 | 0.9501 | 0.9033 | 1.0341 | |||
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13575.174 | 0.0776 | -0.6014 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13575.174 | 0.9277 | 0.9074 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13575.174 | 0.9864 | 0.9828 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13575.174 | 0.8878 | 0.8553 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13575.174 | 0.9544 | 0.9419 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13575.174 | 0.9703 | 0.9624 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13575.174 | 0.9654 | 0.9561 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13575.174 | 0.9743 | 0.9673 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13575.174 | 0.9850 | 0.9810 | 1.5845 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14783.203 | 0.0124 | -0.8093 | 1.8667 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13575.176 | 0.9759 | 0.9672 | 1.4733 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14715.203 | 0.0120 | -0.7771 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14715.203 | 0.0120 | -0.7771 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14715.203 | 0.0143 | -0.7562 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14715.203 | 0.9530 | 0.9528 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14715.203 | 0.0143 | -0.7562 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14715.203 | 0.0100 | -0.7958 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14715.203 | 0.0132 | -0.7658 | 2.0168 |