Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
184A1	NM	Basal	GSK1070916	AURK	AURK	1.33	uM	10002.001	0.7677	0.2227	0.5372
184A1	NM	Basal	GSK461364	PLK1	PLK	0.0000853	uM	10002.001	0.9675	0.8806	0.5372
184A1	NM	Basal	Docetaxel	TUBB	TUBB	0.00064	uM	10002.002	1.0189	1.0398	0.9502
184A1	NM	Basal	Docetaxel	TUBB	TUBB	0.0000256	uM	10002.002	1.0011	1.0024	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	0.000427	uM	10002.002	0.9774	0.9524	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	0.0000853	uM	10002.002	1.0557	1.1175	0.9502
184A1	NM	Basal	Docetaxel	TUBB	TUBB	0.000128	uM	10002.002	1.0033	1.0070	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	0.00213	uM	10002.002	1.0273	1.0576	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	6.67	uM	10002.002	0.7370	0.4505	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	1.33	uM	10002.002	0.6891	0.3516	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	33.3	uM	10002.002	0.7122	0.3992	0.9502
184A1	NM	Basal	Docetaxel	TUBB	TUBB	0.08	uM	10002.002	0.7581	0.4943	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	0.0107	uM	10002.002	0.9247	0.8417	0.9502
184A1	NM	Basal	Docetaxel	TUBB	TUBB	0.4	uM	10002.002	0.6623	0.2962	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	0.0533	uM	10002.002	0.7459	0.4689	0.9502
184A1	NM	Basal	Docetaxel	TUBB	TUBB	0.0032	uM	10002.002	0.9365	0.8666	0.9502
184A1	NM	Basal	Docetaxel	TUBB	TUBB	2	uM	10002.002	0.7677	0.5141	0.9502
184A1	NM	Basal	Docetaxel	TUBB	TUBB	10	uM	10002.002	0.8835	0.7556	0.9502
184A1	NM	Basal	Docetaxel	TUBB	TUBB	0.016	uM	10002.002	0.8470	0.6792	0.9502
184A1	NM	Basal	Taxol	TUBB	TUBB	0.267	uM	10002.002	0.7396	0.4560	0.9502
184A1	NM	Basal	Geldanamycin	HSP90	HSP90	4	uM	10002.012	0.4601	-0.4746	0.5807
184A1	NM	Basal	Geldanamycin	HSP90	HSP90	0.8	uM	10002.012	0.4661	-0.4629	0.5807
184A1	NM	Basal	Geldanamycin	HSP90	HSP90	20	uM	10002.012	0.4490	-0.4963	0.5807
184A1	NM	Basal	Geldanamycin	HSP90	HSP90	100	uM	10002.012	0.4515	-0.4915	0.5807
184A1	NM	Basal	Geldanamycin	HSP90	HSP90	0.16	uM	10002.012	0.4811	-0.4326	0.5807

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)