Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7896.017 | 0.0002 | -0.9995 | 1.0113 | |
| BT-549 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7803.017 | 0.0002 | -0.8801 | 2.9572 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7824.017 | 0.0002 | -0.9871 | 1.6694 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9878.017 | 0.0002 | -0.9967 | 1.3463 | |
| BT-474 | HER2amp | Luminal | Bromopyruvic acid | Hexokinase II | Metabolism | 33.3 | uM | 13125.177 | 0.0001 | -1.0000 | 0.8991 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 172 | uM | 7911.017 | 0.0001 | -0.9915 | 1.6151 | |
| T47DKBLUC | Unknown | Unknown | Bromopyruvic acid | Hexokinase II | Metabolism | 33.3 | uM | 13070.177 | 0.0001 | -0.9999 | 0.9040 |