Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7911.011 | 0.0222 | -0.8108 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7911.011 | 0.0847 | -0.5663 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10124.021 | 0.9527 | 0.9515 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10124.021 | 1.0451 | 1.0451 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10124.021 | 0.0640 | -0.5030 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10124.021 | 0.1483 | -0.2394 | 1.9744 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10147.021 | 1.0245 | 1.0223 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10147.021 | 0.9212 | 0.9263 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10147.021 | 0.9396 | 0.9438 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10147.021 | 0.7611 | 0.7651 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10147.021 | 0.0107 | -0.7489 | 2.1856 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 0.00427 | uM | 10644.136 | 0.9900 | 0.9642 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 2.67 | uM | 10644.136 | 1.0869 | 1.3232 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 13.3 | uM | 10644.136 | 1.0153 | 1.0553 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 333 | uM | 10644.136 | 0.8649 | 0.5406 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 1670 | uM | 10644.136 | 0.1807 | -0.9077 | 0.5562 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7429.102 | 1.0073 | 1.0060 | 2.4347 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7429.102 | 1.0322 | 1.0262 | 2.4347 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7429.102 | 0.9608 | 0.9674 | 2.4347 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7429.102 | 0.9709 | 0.9759 | 2.4347 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7807.042 | 1.0538 | 1.0524 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7807.042 | 1.0390 | 1.0381 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7807.042 | 1.0224 | 1.0220 | 2.0250 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12608.17 | 0.0202 | -0.9465 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12608.17 | 0.0202 | -0.9465 | 1.0776 |