Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10643.142 | 1.0256 | 1.1004 | 0.5166 | |
| MDA-MB-361 | HER2amp | Luminal | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10643.142 | 1.0331 | 1.1300 | 0.5166 | |
| MDA-MB-361 | HER2amp | Luminal | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10643.142 | 1.0153 | 1.0595 | 0.5166 | |
| HCC1569 | HER2amp | Basal A | PD184352 | MEK | MAPK | 33.3 | uM | 10872.155 | 1.0121 | 1.0158 | 1.5288 | |
| HCC1569 | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 12523.155 | 0.9785 | 0.9594 | 1.0583 | |
| HCC1569 | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 12523.155 | 0.9785 | 0.9594 | 1.0583 | |
| HCC1569 | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 12523.155 | 0.9711 | 0.9454 | 1.0583 |