Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 172 | uM | 7911.017 | 0.0001 | -0.9915 | 1.6151 | |
| HBL-100 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7429.09 | 1.0206 | 1.0183 | 2.2456 | |
| HBL-100 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.107 | uM | 7429.09 | 0.9858 | 0.9873 | 2.2456 | |
| HBL-100 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.533 | uM | 7429.09 | 1.0153 | 1.0136 | 2.2456 | |
| HBL-100 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 13.3 | uM | 7429.09 | 1.0002 | 1.0002 | 2.2456 | |
| HBL-100 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 66.7 | uM | 7429.09 | 0.9289 | 0.9353 | 2.2456 | |
| MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7482.091 | 0.8370 | 0.8244 | 1.9368 | |
| MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7482.091 | 0.8115 | 0.7955 | 1.9368 | |
| MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.533 | uM | 7482.091 | 0.2881 | 0.0520 | 1.9368 | |
| MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 2.67 | uM | 7482.091 | 0.4343 | 0.3003 | 1.9368 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7523.091 | 0.9350 | 0.8604 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7523.091 | 0.9329 | 0.8558 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.533 | uM | 7523.091 | 0.8951 | 0.7749 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 2.67 | uM | 7523.091 | 0.8529 | 0.6849 | 0.9283 | |
| T47DKBLUC | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7544.092 | 0.9984 | 0.9971 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7544.092 | 0.9772 | 0.9591 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7544.092 | 0.9145 | 0.8459 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7544.092 | 1.0173 | 1.0310 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | Erlotinib | EGFR | ErbB | 33.3 | uM | 7544.092 | 0.9559 | 0.9208 | 1.1147 | |
| MX1 | Unknown | Unknown | 2-deoxyglucose | 0.00853 | uM | 12667.177 | 1.0963 | 1.3376 | 0.5892 | |||
| MX1 | Unknown | Unknown | 2-deoxyglucose | 0.0427 | uM | 12667.177 | 0.8943 | 0.6545 | 0.5892 | |||
| MX1 | Unknown | Unknown | 2-deoxyglucose | 0.213 | uM | 12667.177 | 1.0184 | 1.0629 | 0.5892 | |||
| MX1 | Unknown | Unknown | 2-deoxyglucose | 1.07 | uM | 12667.177 | 0.6889 | 0.0625 | 0.5892 | |||
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7544.066 | 1.0223 | 1.0408 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7544.066 | 0.9474 | 0.9033 | 1.0898 |