BYL719 KINOMEscan - Dataset (ID:20263)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200009 | ABL1(F317L)-nonphosphorylated | 200009 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317L | nonphosphorylated | Mutation (F317L); Partial length | |
| 200010 | ABL1(F317L)-phosphorylated | 200010 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317L | phosphorylated | Mutation (F317L); Partial length | |
| 200006 | ABL1(F317I)-nonphosphorylated | 200006 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317I | nonphosphorylated | Mutation (F317I); Partial length | |
| 200007 | ABL1(F317I)-phosphorylated | 200007 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317I | phosphorylated | Mutation (F317I); Partial length | |
| 200123 | EGFR(E746-A750del) | 200123 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | E746-A750del | Mutation (E746-A750del); Partial length | ||
| 200327 | PIK3CA(E545K) | 200327 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545K | Mutation (E545K); Partial length | ||
| 200326 | PIK3CA(E545A) | 200326 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545A | Mutation (E545A); Partial length | ||
| 200325 | PIK3CA(E542K) | 200325 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E542K | Mutation (E542K); Partial length | ||
| 200004 | ABL1(E255K)-phosphorylated | 200004 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | E255K | phosphorylated | Mutation (E255K); Partial length | |
| 200170 | FLT3(D835Y) | 200170 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835Y | Mutation (D835Y); Partial length | ||
| 201325 | FLT3(D835V) | 201325 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835V | |||
| 200169 | FLT3(D835H) | 200169 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835H | Mutation (D835H); Partial length | ||
| 200217 | KIT(D816V) | 200217 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | D816V | Mutation (D816V); Partial length | ||
| 200216 | KIT(D816H) | 200216 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | D816H | Mutation (D816H); Partial length | ||
| 200324 | PIK3CA(C420R) | 200324 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | C420R | Mutation (C420R); Partial length | ||
| 200479 | ALK(C1156Y) | 200479 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | C1156Y | |||
| 200215 | KIT(A829P) | 200215 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | A829P | Mutation (A829P); Partial length |