LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (drug combination treatments). Dataset 1 of 2: Cell count and normalized growth rate inhibition values. - Dataset (ID:20259)

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Cell Small Molecule Small Mol 1 Concentration Small Mol 1 Conc Unit Small Molecule 2 Small Mol 2 Concentration Small Mol 2 Conc Unit Biological Replicate Technical Replicate Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Normalized Growth Rate Inhibition Value
BT-20 Alpelisib
3.3333
uM
 Trametinib
0.1235
uM
 2 2 1843 469 5278 -0.5943
BT-20 Dactolisib
0.0412
uM
 NVP-TAE684
0.3704
uM
 2 2 1843 2710 5278 0.2889
BT-20 Dactolisib
0.0412
uM
 Neratinib
0.6415
uM
 2 2 1843 1652 5278 -0.0698
BT-20 Dactolisib
0.0412
uM
 Neratinib
1.1111
uM
 2 2 1843 1580 5278 -0.0968
BT-20 Dactolisib
0.0137
uM
 Saracatinib
0.6415
uM
 2 2 1843 3013 5278 0.3822
BT-20 Alpelisib
0.1235
uM
 Neratinib
0.2138
uM
 2 2 1843 3482 5278 0.5205
BT-20 Alpelisib
0.2138
uM
 Selumetinib
10
uM
 2 2 1843 2781 5278 0.3111
BT-20 Dactolisib
0.0017
uM
 Neratinib
0.3704
uM
 2 2 1843 3836 5278 0.6206
BT-20 Dactolisib
0.0412
uM
 Trametinib
0.1235
uM
 2 2 1843 1505 5278 -0.1253
BT-20 Alpelisib
1.1111
uM
 Saracatinib
0.2138
uM
 2 2 1843 2173 5278 0.1143
BT-20 Dactolisib
0.0137
uM
 Trametinib
1.1111
uM
 2 2 1843 1960 5278 0.0411
BT-20 Dactolisib
0.0047
uM
 Neratinib
0.6415
uM
 2 2 1843 2968 5278 0.3685
BT-20 Alpelisib
0.6415
uM
 NVP-TAE684
3.3333
uM
 2 2 1843 1037 5278 -0.3157
BT-20 Dactolisib
0.0047
uM
 Trametinib
0.1235
uM
 2 2 1843 3343 5278 0.4802
BT-20
0
uM
0
uM
 2 2 1843 5186 5278 0.9769
BT-20 Alpelisib
1.1111
uM
 Lapatinib
10
uM
 2 2 1843 1357 5278 -0.1829
BT-20 Alpelisib
3.3333
uM
 NVP-TAE684
1.1111
uM
 2 2 1843 869 5278 -0.3909
BT-20 Dactolisib
0.0017
uM
 Selumetinib
10
uM
 2 2 1843 3770 5278 0.6022
BT-20 Alpelisib
0.2138
uM
 Neratinib
1.1111
uM
 2 2 1843 2195 5278 0.1218
BT-20
0
uM
0
uM
 2 2 1843 4804 5278 0.8797
BT-20 Alpelisib
0.3704
uM
 Neratinib
0.0713
uM
 2 2 1843 3017 5278 0.3834
BT-20 Dactolisib
0.0047
uM
 Selumetinib
1.1111
uM
 2 2 1843 3558 5278 0.5422
BT-20
0
uM
0
uM
 2 2 1843 4893 5278 0.9026
BT-20 Alpelisib
0.6415
uM
 Neratinib
0.1235
uM
 2 2 1843 2217 5278 0.1292
BT-20
0
uM
0
uM
 2 2 1843 5154 5278 0.9689
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