Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 3 of 3: Calculated dose-response metrics. - Dataset (ID:20258)

Data Columns

  • 20 Data Columns
Name Description Display Name Data Type Unit Precision Readout Type Replicate Comments
gRR2
r^2 for the sigmoidal curve fit to the GR dose-response data
GR r2 Text
gRCurveFit
Formula for the sigmoidal curve fit to the GR dose-response data
GR Curve Fit Text
gRAOC
Integral of GR(c) over the range of concentrations tested (from GR dose-response curve)
GR_AOC Numeric 4
gRHillCoefficient
Maximal slope of the GR dose-response curve
GR Hill Coefficient Numeric 4
gRinf
Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the GR dose-response data
GRinf Numeric 4
gRmax
Normalized growth inhibition rate at the highest tested small molecule concentration (from GR dose-response curve)
GRmax Numeric 4
gEC50
Small molecule concentration that results in 50% efficacy (from GR dose-response curve)
GEC50 Text uM
gR50
Small molecule concentration at which GR(c)=0.5 (from GR dose-response curve)
GR50 Text uM
iCr2
r^2 for the sigmoidal curve fit to the relative cell count dose-response data
IC r2 Text
iCCurveFit
Formula for the sigmoidal curve fit to the relative cell count dose-response data
IC Curve Fit Text
iCAUC
Area under the curve over the range of concentrations tested (from relative cell count dose-response curve)
IC_AUC Numeric 4
iCHillCoefficient
Maximal slope of the relative cell count dose-response curve
IC Hill Coefficient Numeric 4
einf
Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the relative cell count dose-response data
Einf Numeric 4
emax
Relative cell count at the highest tested small molecule concentration (from relative cell count dose-response curve)
Emax Numeric 4
eC50
Small molecule concentration that results in 50% efficacy (from relative cell count dose-response curve)
EC50 Text uM
iC50
Small molecule concentration at which the treated cell count is 50% of the control cell count (from relative cell count dose-response curve)
IC50 Text uM
seedingDensity Seeding Density Numeric 2
replicate Replicate Numeric 0
smallMolecule
Small molecule perturbagen
Small Molecule small_molecule
cell
Cell reagent
Cell cell
  • 20 Data Columns