Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Omipalisib | 0.031623 | uM | 2 | 156.25 | 57.48 | 28.67 | 446.92 | 0.0647 | -0.2202 |
| MCF 10A | 17-AAG | 0.31623 | uM | 7 | 156.25 | 15.92 | 29.00 | 169.42 | 0.1872 | 0.1884 |
| MCF 10A | Lapatinib | 10 | uM | 9 | 156.25 | 46.09 | 29.50 | 260.33 | 0.1133 | -0.1706 |
| BT-20 | Omipalisib | 10 | uM | 3 | 156.25 | 49.48 | 30.33 | 96.33 | 0.3149 | -0.4126 |
| MCF 10A | Omipalisib | 0.31623 | uM | 2 | 625.00 | 277.50 | 30.67 | 3384.25 | 0.0088 | -0.4732 |
| MCF7 | Omipalisib | 0.1 | uM | 1 | 156.25 | 31.46 | 31.00 | 70.42 | 0.4502 | 0.0026 |
| MCF7 | Omipalisib | 0.031623 | uM | 1 | 156.25 | 31.46 | 31.00 | 70.42 | 0.4550 | 0.0093 |
| MCF7 | Omipalisib | 0.31623 | uM | 1 | 156.25 | 31.46 | 31.00 | 70.42 | 0.4374 | -0.0273 |
| MCF7 | Taxol | 0.031623 | uM | 1 | 156.25 | 31.46 | 31.00 | 70.42 | 0.4416 | -0.0150 |
| MCF 10A | Erlotinib | 19.9526 | uM | 7 | 156.25 | 15.92 | 31.00 | 169.42 | 0.1878 | 0.2156 |
| BT-20 | Omipalisib | 0.31623 | uM | 4 | 156.25 | 44.67 | 31.00 | 75.92 | 0.4224 | -0.4277 |
| MCF7 | Omipalisib | 1 | uM | 1 | 156.25 | 31.46 | 31.33 | 70.42 | 0.4407 | -0.0229 |
| BT-20 | NVP-TAE684 | 10 | uM | 4 | 156.25 | 44.67 | 31.67 | 74.08 | 0.4236 | -0.3827 |
| MCF 10A | Omipalisib | 10 | uM | 2 | 312.50 | 134.46 | 32.00 | 1303.25 | 0.0249 | -0.3940 |
| MCF7 | Omipalisib | 0.01 | uM | 1 | 156.25 | 31.46 | 32.33 | 70.42 | 0.4664 | 0.0281 |
| MCF7 | NVP-TAE684 | 0.31623 | uM | 1 | 156.25 | 31.46 | 32.33 | 85.83 | 0.3843 | 0.0102 |
| MCF7 | Etoposide | 10 | uM | 1 | 156.25 | 31.46 | 33.00 | 85.83 | 0.4217 | 0.0670 |
| MCF7 | 17-AAG | 3.1623 | uM | 10 | 156.25 | 46.73 | 33.67 | 104.00 | 0.3304 | -0.2501 |
| MCF7 | Etoposide | 19.9526 | uM | 1 | 156.25 | 31.46 | 33.67 | 85.83 | 0.4354 | 0.0996 |
| MCF 10A | 17-AAG | 0.1 | uM | 7 | 156.25 | 15.92 | 34.00 | 169.42 | 0.2099 | 0.2509 |
| MCF7 | NVP-TAE684 | 3.1623 | uM | 1 | 156.25 | 31.46 | 34.67 | 85.83 | 0.4320 | 0.1013 |
| BT-20 | Omipalisib | 10 | uM | 5 | 156.25 | 29.46 | 34.67 | 134.00 | 0.2566 | 0.0666 |
| MCF7 | Taxol | 0.01 | uM | 1 | 156.25 | 31.46 | 34.67 | 70.42 | 0.5046 | 0.1068 |
| MCF7 | Omipalisib | 3.1623 | uM | 1 | 156.25 | 31.46 | 34.67 | 70.42 | 0.5101 | 0.1173 |
| BT-20 | Omipalisib | 1 | uM | 4 | 156.25 | 44.67 | 35.00 | 75.92 | 0.4793 | -0.2863 |