Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Lapatinib | 0.31623 | uM | 8 | 2500.00 | 1235.42 | 11740.00 | 11667.75 | 1.0062 | 1.0038 |
| MCF 10A | PLX-4720 | 10 | uM | 5 | 5000.00 | 2329.88 | 11744.00 | 9541.50 | 1.2308 | 1.2150 |
| MCF 10A | Lapatinib | 0.0033113 | uM | 7 | 2500.00 | 469.42 | 11744.00 | 11060.25 | 1.0618 | 1.0265 |
| MCF 10A | 17-AAG | 0.0001 | uM | 8 | 5000.00 | 1432.23 | 11748.00 | 11858.50 | 0.9907 | 0.9939 |
| MCF 10A | Linsitinib | 0.0033113 | uM | 8 | 2500.00 | 1235.42 | 11749.00 | 11547.50 | 1.0174 | 1.0108 |
| MCF 10A | 0 | uM | 8 | 2500.00 | 1235.42 | 11756.00 | 11667.75 | 1.0076 | 1.0047 | |
| MCF 10A | Erlotinib | 0.031623 | uM | 9 | 2500.00 | 860.55 | 11757.00 | 10674.25 | 1.1014 | 1.0539 |
| MCF 10A | 0 | uM | 2 | 5000.00 | 3410.67 | 11757.00 | 12101.00 | 0.9716 | 0.9687 | |
| MCF 10A | 0 | uM | 2 | 5000.00 | 3410.67 | 11759.00 | 12101.00 | 0.9717 | 0.9689 | |
| MCF 10A | Lapatinib | 0.1 | uM | 9 | 5000.00 | 2099.14 | 11761.00 | 11494.75 | 1.0232 | 1.0188 |
| MCF 10A | PLX-4720 | 3.1623 | uM | 6 | 2500.00 | 1235.29 | 11762.00 | 10577.75 | 1.1120 | 1.0697 |
| MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11766.00 | 11890.75 | 0.9895 | 0.9916 | |
| MCF 10A | Nilotinib | 0.01 | uM | 5 | 1250.00 | 996.83 | 11769.00 | 10779.25 | 1.0918 | 1.0518 |
| MCF 10A | 0 | uM | 8 | 5000.00 | 1432.23 | 11772.00 | 11782.50 | 0.9991 | 0.9994 | |
| MCF 10A | Lapatinib | 0.031623 | uM | 8 | 5000.00 | 1432.23 | 11774.00 | 11858.50 | 0.9929 | 0.9953 |
| MCF 10A | 0 | uM | 9 | 5000.00 | 2099.14 | 11779.00 | 11908.75 | 0.9891 | 0.9913 | |
| MCF 10A | Lapatinib | 0.031623 | uM | 7 | 1250.00 | 252.38 | 11780.00 | 11119.50 | 1.0594 | 1.0212 |
| MCF 10A | PLX-4720 | 19.9526 | uM | 5 | 5000.00 | 2329.88 | 11784.00 | 9494.75 | 1.2411 | 1.2249 |
| MCF 10A | 17-AAG | 0.000302 | uM | 8 | 5000.00 | 1432.23 | 11786.00 | 11858.50 | 0.9939 | 0.9960 |
| MCF 10A | 0 | uM | 8 | 5000.00 | 1432.23 | 11786.00 | 11858.50 | 0.9939 | 0.9960 | |
| MCF 10A | Lapatinib | 0.0033113 | uM | 8 | 2500.00 | 1235.42 | 11786.00 | 11524.50 | 1.0227 | 1.0140 |
| MCF 10A | 0 | uM | 8 | 5000.00 | 1432.23 | 11786.00 | 11858.50 | 0.9939 | 0.9960 | |
| MCF 10A | 0 | uM | 8 | 2500.00 | 1235.42 | 11786.00 | 11667.75 | 1.0101 | 1.0062 | |
| MCF 10A | 0 | uM | 2 | 5000.00 | 3410.67 | 11796.00 | 12101.00 | 0.9748 | 0.9723 | |
| MCF 10A | Erlotinib | 0.01 | uM | 8 | 5000.00 | 1432.23 | 11799.00 | 11858.50 | 0.9950 | 0.9967 |