Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | Nilotinib | 3.1623 | uM | 11 | 2500.00 | 1224.73 | 2564.00 | 2645.50 | 0.9692 | 0.9445 |
Hs 578T | Palbociclib | 3.1623 | uM | 10 | 5000.00 | 2253.55 | 2448.00 | 5630.25 | 0.4348 | 0.0647 |
SK-BR-3 | Lapatinib | 3.1623 | uM | 9 | 1250.00 | 830.55 | 614.00 | 1922.63 | 0.3194 | -0.2208 |
MCF7 | Palbociclib | 3.1623 | uM | 10 | 5000.00 | 1515.32 | 2504.00 | 5888.75 | 0.4252 | 0.2924 |
MDA-MB-231 | Lapatinib | 3.1623 | uM | 10 | 312.50 | 120.45 | 753.00 | 507.00 | 1.4852 | 1.4204 |
SK-BR-3 | Linsitinib | 3.1623 | uM | 9 | 1250.00 | 830.55 | 1582.00 | 1922.63 | 0.8228 | 0.7025 |
SK-BR-3 | Linsitinib | 3.1623 | uM | 9 | 1250.00 | 830.55 | 1737.00 | 1981.25 | 0.8767 | 0.8008 |
Hs 578T | 17-AAG | 3.1623 | uM | 10 | 625.00 | 252.14 | 327.00 | 1708.00 | 0.1915 | 0.0988 |
MCF7 | Erlotinib | 3.1623 | uM | 10 | 2500.00 | 703.32 | 2881.00 | 2590.50 | 1.1121 | 1.1163 |
MCF7 | Linsitinib | 3.1623 | uM | 10 | 2500.00 | 703.32 | 1178.00 | 2590.50 | 0.4547 | 0.3155 |
SK-BR-3 | Erlotinib | 3.1623 | uM | 9 | 5000.00 | 3570.27 | 5331.00 | 6344.00 | 0.8403 | 0.6216 |
MDA-MB-231 | Omipalisib | 3.1623 | uM | 10 | 312.50 | 120.45 | 104.00 | 227.50 | 0.4571 | -0.1480 |
SK-BR-3 | Linsitinib | 3.1623 | uM | 9 | 2500.00 | 1861.36 | 3446.00 | 3777.75 | 0.9122 | 0.8279 |
Hs 578T | Palbociclib | 3.1623 | uM | 11 | 2500.00 | 1224.73 | 1297.00 | 2645.50 | 0.4903 | 0.0530 |
MDA-MB-231 | Nilotinib | 3.1623 | uM | 10 | 312.50 | 120.45 | 150.00 | 227.50 | 0.6593 | 0.2701 |
SK-BR-3 | Erlotinib | 3.1623 | uM | 9 | 1250.00 | 830.55 | 1457.00 | 1922.63 | 0.7578 | 0.5907 |
SK-BR-3 | Lapatinib | 3.1623 | uM | 9 | 625.00 | 414.82 | 441.00 | 795.25 | 0.5545 | 0.0674 |
MCF7 | Lapatinib | 3.1623 | uM | 10 | 2500.00 | 703.32 | 2413.00 | 2590.50 | 0.9315 | 0.9259 |
MCF7 | Lapatinib | 3.1623 | uM | 10 | 625.00 | 172.23 | 702.00 | 459.25 | 1.5286 | 1.6994 |
MCF7 | Palbociclib | 3.1623 | uM | 11 | 1250.00 | 353.09 | 586.00 | 1219.50 | 0.4805 | 0.3275 |
MCF7 | 17-AAG | 3.1623 | uM | 10 | 5000.00 | 1515.32 | 1516.00 | 5533.00 | 0.2740 | 0.0002 |
Hs 578T | Omipalisib | 3.1623 | uM | 11 | 2500.00 | 1224.73 | 731.00 | 2645.50 | 0.2763 | -0.3715 |
Hs 578T | Linsitinib | 3.1623 | uM | 10 | 1250.00 | 573.23 | 3107.00 | 2950.00 | 1.0532 | 1.0444 |
SK-BR-3 | Lapatinib | 3.1623 | uM | 9 | 2500.00 | 1861.36 | 1582.00 | 3777.75 | 0.4188 | -0.1472 |
MCF7 | Omipalisib | 3.1623 | uM | 11 | 1250.00 | 353.09 | 341.00 | 1219.50 | 0.2796 | -0.0193 |