Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF7 | Nilotinib | 1 | uM | 10 | 156.25 | 46.73 | 218.00 | 100.75 | 2.1638 | 3.0128 |
MCF 10A | Linsitinib | 0.01 | uM | 8 | 156.25 | 23.19 | 754.00 | 348.25 | 2.1651 | 1.4370 |
SK-BR-3 | Erlotinib | 19.9526 | uM | 9 | 156.25 | 92.36 | 267.00 | 123.25 | 2.1663 | 11.8141 |
MDA-MB-231 | Lapatinib | 0.031623 | uM | 10 | 156.25 | 67.09 | 501.00 | 231.00 | 2.1688 | 2.0869 |
MCF7 | Etoposide | 0.31623 | uM | 1 | 156.25 | 31.46 | 147.00 | 67.75 | 2.1697 | 3.0270 |
BT-20 | Erlotinib | 19.9526 | uM | 8 | 312.50 | 129.17 | 439.00 | 202.25 | 2.1706 | 5.6270 |
MCF7 | 0 | uM | 1 | 156.25 | 31.46 | 104.00 | 47.86 | 2.1728 | 6.2053 | |
MCF 10A | Lapatinib | 0.031623 | uM | 8 | 156.25 | 23.19 | 851.00 | 390.75 | 2.1779 | 1.4209 |
SK-BR-3 | 0 | uM | 4 | 156.25 | 63.10 | 148.00 | 67.75 | 2.1845 | 4093.9433 | |
SK-BR-3 | NVP-TAE684 | 0.0033113 | uM | 4 | 156.25 | 63.10 | 148.00 | 67.75 | 2.1845 | 4093.9433 |
Hs 578T | Palbociclib | 19.9526 | uM | 10 | 156.25 | 66.59 | 211.00 | 96.50 | 2.1865 | 7.6267 |
SK-BR-3 | Erlotinib | 19.9526 | uM | 9 | 156.25 | 92.36 | 246.00 | 112.50 | 2.1867 | 30.2771 |
Hs 578T | Nilotinib | 19.9526 | uM | 11 | 625.00 | 252.14 | 1183.00 | 541.00 | 2.1867 | 3.0694 |
MCF7 | 0 | uM | 1 | 156.25 | 31.46 | 149.00 | 67.75 | 2.1993 | 3.0765 | |
MCF 10A | 0 | uM | 8 | 156.25 | 23.19 | 768.00 | 348.25 | 2.2053 | 1.4485 | |
MCF 10A | 0 | uM | 2 | 156.25 | 57.48 | 744.00 | 337.00 | 2.2077 | 1.7279 | |
MCF 10A | Linsitinib | 0.01 | uM | 9 | 156.25 | 46.09 | 626.00 | 283.50 | 2.2081 | 1.7058 |
SK-BR-3 | 0 | uM | 4 | 156.25 | 63.10 | 150.00 | 67.75 | 2.2140 | 4666.9849 | |
MCF 10A | 0 | uM | 2 | 156.25 | 57.48 | 747.00 | 337.00 | 2.2166 | 1.7322 | |
MCF 10A | Linsitinib | 0.031623 | uM | 7 | 156.25 | 15.92 | 297.00 | 133.50 | 2.2247 | 1.5955 |
Hs 578T | 0 | uM | 1 | 5000.00 | 2308.21 | 1866.00 | 837.00 | 2.2294 | 0.1564 | |
MCF7 | 0 | uM | 1 | 156.25 | 31.46 | 169.00 | 75.55 | 2.2371 | 2.7818 | |
MCF7 | 0 | uM | 1 | 156.25 | 31.46 | 145.00 | 64.75 | 2.2394 | 3.3374 | |
SK-BR-3 | 0 | uM | 3 | 156.25 | 80.34 | 167.00 | 74.50 | 2.2416 | -0.9988 | |
Hs 578T | Taxol | 0.00033113 | uM | 10 | 156.25 | 66.59 | 217.00 | 96.50 | 2.2487 | 8.0907 |