LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A | CGP60474 | 1.11 | uM | LJP6 | 0.0340 | 0.0074 | -0.2586 | 0.1276 |
| Hs 578T | Brivanib | 0.37 | uM | LJP5 | 0.9610 | 0.0074 | 0.9628 | 0.0065 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 0.3228 | 0.0074 | 0.0667 | 0.0162 |
| MCF 10A | Withaferin A | 0.04 | uM | LJP6 | 1.0008 | 0.0074 | 1.0008 | 0.0048 |
| MCF 10A | AZD 5438 | 10 | uM | LJP6 | 0.0458 | 0.0074 | -0.1882 | 0.1091 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 1.0265 | 0.0074 | 1.0149 | 0.0033 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP6 | 0.4072 | 0.0075 | 0.0036 | 0.0592 |
| Hs 578T | Brivanib | 1.11 | uM | LJP5 | 0.9335 | 0.0075 | 0.9364 | 0.0035 |
| BT-20 | KIN001-043 | 0.12 | uM | LJP6 | 0.9518 | 0.0075 | 0.9406 | 0.0106 |
| MCF 10A | PF431396 | 10 | uM | LJP5 | 0.0536 | 0.0075 | -0.1536 | 0.0942 |
| SK-BR-3 | Lapatinib | 3.33 | uM | LJP6 | 0.4076 | 0.0076 | 0.0032 | 0.0750 |
| Hs 578T | Dovitinib | 0.04 | uM | LJP5 | 0.7952 | 0.0076 | 0.7912 | 0.0272 |
| BT-20 | SU11274 | 1.11 | uM | LJP5 | 0.9338 | 0.0076 | 0.9217 | 0.0084 |
| Hs 578T | YM 201636 | 0.12 | uM | LJP5 | 0.9828 | 0.0076 | 0.9843 | 0.0072 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 0.9809 | 0.0076 | 0.9782 | 0.0096 |
| MCF7 | PF477736 | 1.11 | uM | LJP5 | 0.4034 | 0.0076 | 0.2350 | 0.0183 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 0.0311 | 0.0076 | -0.2815 | 0.1362 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 0.0307 | 0.0077 | -0.2813 | 0.1364 |
| BT-20 | Sigma A6730 | 0.12 | uM | LJP5 | 0.8769 | 0.0078 | 0.8512 | 0.0149 |
| SK-BR-3 | HG-5-88-01 | 0.37 | uM | LJP6 | 0.7977 | 0.0078 | 0.6777 | 0.0423 |
| MDA-MB-231 | SB590885 | 0.04 | uM | LJP5 | 0.9954 | 0.0078 | 0.9939 | 0.0078 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP6 | 0.3685 | 0.0078 | -0.0702 | 0.0604 |
| MCF 10A | GW843682X | 3.33 | uM | LJP6 | 0.0713 | 0.0078 | -0.0733 | 0.0767 |
| BT-20 | PI103 | 10 | uM | LJP6 | 0.2577 | 0.0079 | -0.1150 | 0.0193 |
| MCF 10A | Seliciclib | 0.12 | uM | LJP5 | 0.9664 | 0.0079 | 0.9805 | 0.0038 |