LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| BT-20 | SNS-032 | 0.37 | uM | LJP6 | 0.2008 | 0.0109 | -0.2389 | 0.0389 |
| MDA-MB-231 | Alvocidib | 0.12 | uM | LJP6 | 0.1573 | 0.0200 | -0.2388 | 0.0716 |
| MDA-MB-231 | Dasatinib | 1.11 | uM | LJP6 | 0.1569 | 0.0107 | -0.2385 | 0.0298 |
| MCF 10A | CGP60474 | 0.37 | uM | LJP6 | 0.0377 | 0.0087 | -0.2385 | 0.1342 |
| MDA-MB-231 | A443654 | 3.33 | uM | LJP6 | 0.1613 | 0.0390 | -0.2376 | 0.1110 |
| MDA-MB-231 | WZ3105 | 1.11 | uM | LJP5 | 0.1572 | 0.0336 | -0.2369 | 0.0946 |
| MCF 10A | Withaferin A | 10 | uM | LJP5 | 0.0381 | 0.0093 | -0.2366 | 0.1188 |
| MDA-MB-231 | WZ3105 | 0.37 | uM | LJP5 | 0.1577 | 0.0336 | -0.2352 | 0.0931 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 0.2857 | 0.0331 | -0.2351 | 0.1146 |
| SK-BR-3 | XMD16-144 | 10 | uM | LJP5 | 0.2699 | 0.0131 | -0.2349 | 0.0851 |
| SK-BR-3 | CGP60474 | 1.11 | uM | LJP5 | 0.2719 | 0.0300 | -0.2328 | 0.1176 |
| MDA-MB-231 | WZ3105 | 3.33 | uM | LJP5 | 0.1573 | 0.0256 | -0.2325 | 0.0722 |
| MDA-MB-231 | WZ3105 | 0.12 | uM | LJP5 | 0.1584 | 0.0315 | -0.2324 | 0.0882 |
| SK-BR-3 | NVP-TAE684 | 10 | uM | LJP6 | 0.2886 | 0.0539 | -0.2321 | 0.0394 |
| Hs 578T | Buparlisib | 10 | uM | LJP5 | 0.1362 | 0.0333 | -0.2313 | 0.0527 |
| SK-BR-3 | QL-X-138 | 10 | uM | LJP6 | 0.2877 | 0.0304 | -0.2311 | 0.1240 |
| MDA-MB-231 | SNS-032 | 1.11 | uM | LJP6 | 0.1615 | 0.0265 | -0.2303 | 0.0878 |
| MDA-MB-231 | WZ3105 | 0.04 | uM | LJP5 | 0.1588 | 0.0273 | -0.2300 | 0.0776 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 0.1632 | 0.0302 | -0.2285 | 0.0990 |
| MDA-MB-231 | NVP-TAE684 | 10 | uM | LJP6 | 0.1656 | 0.0395 | -0.2282 | 0.1224 |
| MDA-MB-231 | Dasatinib | 1.11 | uM | LJP5 | 0.1577 | 0.0149 | -0.2279 | 0.0395 |
| MCF 10A | Celastrol | 3.33 | uM | LJP6 | 0.0380 | 0.0025 | -0.2279 | 0.1107 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 0.2737 | 0.0088 | -0.2272 | 0.0554 |
| SK-BR-3 | WZ3105 | 10 | uM | LJP5 | 0.2754 | 0.0453 | -0.2266 | 0.1115 |
| MDA-MB-231 | CGP60474 | 0.37 | uM | LJP5 | 0.1599 | 0.0267 | -0.2264 | 0.0748 |