LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF7 Barasertib
10
uM
LJP5
 0.3319 0.0252 0.1133 0.0129
MCF7 Vemurafenib
0.04
uM
LJP5
 0.9809 0.0076 0.9782 0.0096
MCF7 Vemurafenib
0.12
uM
LJP5
 1.0142 0.0120 1.0156 0.0136
MCF7 Vemurafenib
0.37
uM
LJP5
 1.0307 0.0088 1.0323 0.0084
MCF7 Vemurafenib
1.11
uM
LJP5
 1.0104 0.0268 1.0081 0.0267
MCF7 Vemurafenib
3.33
uM
LJP5
 0.9986 0.0116 0.9985 0.0130
MCF7 Vemurafenib
10
uM
LJP5
 0.8750 0.0398 0.8580 0.0494
MCF7 Enzastaurin
0.04
uM
LJP5
 0.9831 0.0285 0.9785 0.0298
MCF7 Enzastaurin
0.12
uM
LJP5
 0.9988 0.0181 0.9989 0.0200
MCF7 Enzastaurin
0.37
uM
LJP5
 1.0100 0.0192 1.0087 0.0204
MCF7 Enzastaurin
1.11
uM
LJP5
 0.9518 0.0194 0.9458 0.0226
MCF7 Enzastaurin
3.33
uM
LJP5
 0.9459 0.0437 0.9363 0.0482
MCF7 Enzastaurin
10
uM
LJP5
 0.7547 0.1436 0.6929 0.1778
MCF7 Palbociclib
0.04
uM
LJP6
 0.7469 0.0340 0.6960 0.0521
MCF7 Palbociclib
0.12
uM
LJP6
 0.6383 0.0434 0.5519 0.0729
MCF7 Palbociclib
0.37
uM
LJP6
 0.5646 0.0511 0.4472 0.0896
MCF7 Palbociclib
1.11
uM
LJP6
 0.5003 0.0347 0.3564 0.0730
MCF7 Palbociclib
3.33
uM
LJP6
 0.4741 0.0063 0.3199 0.0316
MCF7 Palbociclib
10
uM
LJP6
 0.4571 0.0152 0.2944 0.0140
MCF7 PF562271
0.04
uM
LJP6
 0.8739 0.0040 0.8557 0.0025
MCF7 PF562271
0.12
uM
LJP6
 0.7944 0.0213 0.7587 0.0310
MCF7 PF562271
0.37
uM
LJP6
 0.6185 0.0152 0.5291 0.0380
MCF7 PF562271
1.11
uM
LJP6
 0.4316 0.0202 0.2511 0.0542
MCF7 PF562271
3.33
uM
LJP6
 0.2503 0.0161 -0.0743 0.0252
MCF7 PF562271
10
uM
LJP6
 0.1502 0.0265 -0.3091 0.0397