LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 1694 11824 11217 1.0544 1.0390
MCF 10A Celastrol
0.04
uM
LJP6
 72
hr
 1694 11896 11217 1.0605 1.0436
MCF 10A Foretinib
0.04
uM
LJP5
 72
hr
 1694 11930 11103 1.0746 1.0537
MCF 10A Enzastaurin
10
uM
LJP5
 72
hr
 1694 12028 11103 1.0833 1.0598
MCF 10A PLX-4720
3.33
uM
LJP5
 72
hr
 1694 12034 11103 1.0839 1.0602
MCF 10A QL-X-138
0.12
uM
LJP6
 72
hr
 1694 12035 11217 1.0729 1.0523
MCF 10A Sorafenib
0.04
uM
LJP6
 72
hr
 1694 12063 11217 1.0756 1.0540
MCF 10A Sirolimus
0.04
uM
LJP6
 72
hr
 1694 12244 11217 1.0916 1.0653
MCF 10A QL-X-138
0.04
uM
LJP6
 72
hr
 1694 12300 11217 1.0965 1.0686
MCF 10A Sirolimus
0.12
uM
LJP6
 72
hr
 1694 12338 11217 1.0999 1.0710
MCF 10A Celastrol
0.12
uM
LJP6
 72
hr
 1694 12410 11217 1.1065 1.0756
MCF 10A Sirolimus
10
uM
LJP6
 72
hr
 1694 12441 11217 1.1091 1.0774
MCF 10A Sirolimus
1.11
uM
LJP6
 72
hr
 1694 12479 11217 1.1126 1.0798
MCF 10A Sirolimus
0.37
uM
LJP6
 72
hr
 1694 12534 11217 1.1174 1.0831
MCF 10A Sirolimus
3.33
uM
LJP6
 72
hr
 1694 12704 11217 1.1326 1.0934