LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Sirolimus | 3.33 | uM | LJP6 | 72 | hr | 1694 | 12704 | 11217 | 1.1326 | 1.0934 |
| MCF 10A | Sirolimus | 0.37 | uM | LJP6 | 72 | hr | 1694 | 12534 | 11217 | 1.1174 | 1.0831 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 1694 | 12479 | 11217 | 1.1126 | 1.0798 |
| MCF 10A | Sirolimus | 10 | uM | LJP6 | 72 | hr | 1694 | 12441 | 11217 | 1.1091 | 1.0774 |
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 1694 | 12410 | 11217 | 1.1065 | 1.0756 |
| MCF 10A | Sirolimus | 0.12 | uM | LJP6 | 72 | hr | 1694 | 12338 | 11217 | 1.0999 | 1.0710 |
| MCF 10A | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 1694 | 12300 | 11217 | 1.0965 | 1.0686 |
| MCF 10A | Sirolimus | 0.04 | uM | LJP6 | 72 | hr | 1694 | 12244 | 11217 | 1.0916 | 1.0653 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 72 | hr | 1694 | 12063 | 11217 | 1.0756 | 1.0540 |
| MCF 10A | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 12035 | 11217 | 1.0729 | 1.0523 |
| MCF 10A | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 12034 | 11103 | 1.0839 | 1.0602 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 72 | hr | 1694 | 12028 | 11103 | 1.0833 | 1.0598 |
| MCF 10A | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11930 | 11103 | 1.0746 | 1.0537 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11896 | 11217 | 1.0605 | 1.0436 |
| MCF 10A | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11824 | 11217 | 1.0544 | 1.0390 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11792 | 11217 | 1.0512 | 1.0369 |
| MCF 10A | CHIR-99021 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11724 | 11217 | 1.0453 | 1.0327 |
| MCF 10A | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11701 | 11103 | 1.0538 | 1.0389 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11701 | 11217 | 1.0431 | 1.0312 |
| MCF 10A | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11668 | 11103 | 1.0509 | 1.0368 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 72 | hr | 1694 | 11663 | 11103 | 1.0504 | 1.0365 |
| MCF 10A | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11662 | 11217 | 1.0398 | 1.0288 |
| MCF 10A | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11652 | 11217 | 1.0389 | 1.0281 |
| MCF 10A | JW-7-24-1 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11636 | 11217 | 1.0373 | 1.0270 |
| MCF 10A | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11631 | 11217 | 1.0372 | 1.0267 |