LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Imatinib
0.37
uM
LJP6
 1
N16
 72
hr
 929 3318 3185 1.0417 1.0465
Hs 578T Dasatinib
0.37
uM
LJP6
 1
I04
 72
hr
 929 1150 3185 0.3610 0.1274
Hs 578T WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 929 1193 3185 0.3745 0.1510
Hs 578T SNS-032
0.37
uM
LJP6
 1
H16
 72
hr
 929 672 3185 0.2110 -0.1667
Hs 578T Dasatinib
3.33
uM
LJP6
 1
I02
 72
hr
 929 1032 3185 0.3240 0.0608
Hs 578T PD173074
0.12
uM
LJP6
 1
I11
 72
hr
 929 2756 3185 0.8653 0.8436
Hs 578T BI-2536
0.37
uM
LJP6
 1
D16
 72
hr
 929 993 3185 0.3118 0.0380
Hs 578T AT-7519
3.33
uM
LJP6
 1
K02
 72
hr
 929 731 3185 0.2295 -0.1263
Hs 578T Dasatinib
10
uM
LJP6
 1
I01
 72
hr
 929 807 3185 0.2534 -0.0763
Hs 578T Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 929 3266 3185 1.0254 1.0284
Hs 578T Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 929 4036 3185 1.2671 1.2850
Hs 578T Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 929 2318 3185 0.7277 0.6725
Hs 578T Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 929 3478 3185 1.0919 1.1014
Hs 578T AT-7519
0.12
uM
LJP6
 1
K05
 72
hr
 929 2750 3185 0.8634 0.8413
Hs 578T AT-7519
0.04
uM
LJP6
 1
K06
 72
hr
 929 3195 3185 1.0031 1.0035
Hs 578T NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 929 2873 3185 0.9020 0.8872
Hs 578T R406
3.33
uM
LJP6
 1
C14
 72
hr
 929 2179 3185 0.6841 0.6153
Hs 578T AT-7519
0.37
uM
LJP6
 1
K04
 72
hr
 929 923 3185 0.2898 -0.0038
Hs 578T Imatinib
10
uM
LJP6
 1
N13
 72
hr
 929 3509 3185 1.1017 1.1120
Hs 578T AT-7519
1.11
uM
LJP6
 1
K03
 72
hr
 929 897 3185 0.2816 -0.0197
Hs 578T AZD7762
0.04
uM
LJP6
 1
L06
 72
hr
 929 1738 3185 0.5457 0.4223
Hs 578T AT-7519
10
uM
LJP6
 1
K01
 72
hr
 929 662 3185 0.2078 -0.1737
Hs 578T AZD7762
3.33
uM
LJP6
 1
L02
 72
hr
 929 866 3185 0.2719 -0.0389
Hs 578T Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 929 2594 3185 0.8144 0.7818
Hs 578T Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 929 2975 3185 0.9340 0.9246