LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 1235 1756 4126 0.4256 0.2240
MCF7 Dasatinib
0.04
uM
LJP6
 1
I06
 72
hr
 1235 1192 3974 0.2999 -0.0210
MCF7 Dasatinib
0.04
uM
LJP6
 2
I06
 72
hr
 1235 1074 4070 0.2639 -0.0782
MCF7 Dasatinib
0.04
uM
LJP6
 3
I06
 72
hr
 1235 1116 4126 0.2705 -0.0567
MCF7 Dasatinib
0.04
uM
LJP5
 1
D06
 72
hr
 1235 2903 4119 0.7048 0.6352
MCF7 Dasatinib
0.04
uM
LJP5
 2
D06
 72
hr
 1235 2660 4356 0.6106 0.5248
MCF7 Dasatinib
0.04
uM
LJP5
 3
D06
 72
hr
 1235 2301 4326 0.5319 0.4105
MCF7 Alvocidib
0.04
uM
LJP6
 3
A18
 72
hr
 1235 1089 4126 0.2639 -0.0699
MCF7 PLX-4720
0.04
uM
LJP5
 2
K06
 72
hr
 1235 4841 4356 1.1113 1.1195
MCF7 BX-912
0.04
uM
LJP5
 3
L24
 72
hr
 1235 3831 4326 0.8855 0.8699
MCF7 Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 1235 4325 4356 0.9928 0.9921
MCF7 Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 1235 3749 4326 0.8665 0.8477
MCF7 SB590885
0.04
uM
LJP5
 3
L18
 72
hr
 1235 4523 4326 1.0454 1.0498
MCF7 Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 1235 2819 3974 0.7093 0.6314
MCF7 BMS345541
0.04
uM
LJP6
 1
D06
 72
hr
 1235 4308 3974 1.0840 1.0980
MCF7 Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 1235 3458 4126 0.8380 0.8069
MCF7 SB590885
0.04
uM
LJP5
 2
L18
 72
hr
 1235 4753 4356 1.0911 1.0982
MCF7 PF562271
0.04
uM
LJP6
 2
F18
 72
hr
 1235 3794 4070 0.9321 0.9199
MCF7 Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 1235 1361 4326 0.3146 0.0550
MCF7 SB590885
0.04
uM
LJP5
 1
L18
 72
hr
 1235 3870 4119 0.9395 0.9294
MCF7 CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 1235 643 4126 0.1558 -0.3129
MCF7 CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 1235 661 4070 0.1624 -0.3048
MCF7 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 1235 1841 4126 0.4462 0.2577
MCF7 XL147
0.04
uM
LJP5
 2
G12
 72
hr
 1235 4683 4356 1.0750 1.0812
MCF7 XL147
0.04
uM
LJP5
 1
G12
 72
hr
 1235 4696 4119 1.1400 1.1567