LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | WYE-125132 | 0.12 | uM | LJP6 | 1 | L11 | 72 | hr | 1235 | 1831 | 3974 | 0.4607 | 0.2629 |
| MCF7 | Dasatinib | 0.04 | uM | LJP6 | 1 | I06 | 72 | hr | 1235 | 1192 | 3974 | 0.2999 | -0.0210 |
| MCF7 | Alvocidib | 0.04 | uM | LJP6 | 1 | A18 | 72 | hr | 1235 | 1106 | 3974 | 0.2783 | -0.0635 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 1 | A22 | 72 | hr | 1235 | 2423 | 4119 | 0.5882 | 0.4736 |
| MCF7 | Dasatinib | 0.04 | uM | LJP5 | 1 | D06 | 72 | hr | 1235 | 2903 | 4119 | 0.7048 | 0.6352 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 1 | A09 | 72 | hr | 1235 | 1397 | 3974 | 0.3515 | 0.0757 |
| MCF7 | Dasatinib | 3.33 | uM | LJP5 | 1 | D02 | 72 | hr | 1235 | 954 | 4119 | 0.2316 | -0.1382 |
| MCF7 | Dasatinib | 0.12 | uM | LJP6 | 1 | I05 | 72 | hr | 1235 | 1079 | 3974 | 0.2715 | -0.0772 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 1 | A17 | 72 | hr | 1235 | 722 | 3974 | 0.1817 | -0.2729 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 1 | A19 | 72 | hr | 1235 | 666 | 4119 | 0.1617 | -0.2993 |
| MCF7 | Dasatinib | 0.12 | uM | LJP5 | 1 | D05 | 72 | hr | 1235 | 1295 | 4119 | 0.3144 | 0.0275 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 1 | J01 | 72 | hr | 1235 | 734 | 4119 | 0.1782 | -0.2589 |
| MCF7 | Dasatinib | 10 | uM | LJP6 | 1 | I01 | 72 | hr | 1235 | 767 | 3974 | 0.1930 | -0.2463 |
| MCF7 | Dasatinib | 0.37 | uM | LJP6 | 1 | I04 | 72 | hr | 1235 | 922 | 3974 | 0.2320 | -0.1594 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 1235 | 677 | 3974 | 0.1704 | -0.3001 |
| MCF7 | BMS345541 | 10 | uM | LJP6 | 1 | D01 | 72 | hr | 1235 | 758 | 3974 | 0.1907 | -0.2516 |
| MCF7 | Dasatinib | 0.37 | uM | LJP5 | 1 | D04 | 72 | hr | 1235 | 931 | 4119 | 0.2260 | -0.1503 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 1 | A08 | 72 | hr | 1235 | 1388 | 3974 | 0.3493 | 0.0715 |
| MCF7 | KIN001-043 | 0.37 | uM | LJP6 | 1 | C10 | 72 | hr | 1235 | 3739 | 3974 | 0.9408 | 0.9289 |
| MCF7 | Dasatinib | 1.11 | uM | LJP6 | 1 | I03 | 72 | hr | 1235 | 1208 | 3974 | 0.3040 | -0.0132 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 1235 | 609 | 3974 | 0.1532 | -0.3427 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 1 | B17 | 72 | hr | 1235 | 1405 | 4119 | 0.3411 | 0.0769 |
| MCF7 | Dasatinib | 1.11 | uM | LJP5 | 1 | D03 | 72 | hr | 1235 | 1004 | 4119 | 0.2437 | -0.1125 |
| MCF7 | Barasertib | 3.33 | uM | LJP5 | 1 | D08 | 72 | hr | 1235 | 1630 | 4119 | 0.3957 | 0.1730 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 1 | D09 | 72 | hr | 1235 | 1541 | 4119 | 0.3741 | 0.1357 |