LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 3 | C20 | 72 | hr | 1235 | 671 | 4126 | 0.1626 | -0.2959 |
| BT-20 | Withaferin A | 3.33 | uM | LJP5 | 2 | G14 | 72 | hr | 1657 | 895 | 5610 | 0.1595 | -0.2956 |
| SK-BR-3 | LDN-193189 | 3.33 | uM | LJP5 | 2 | G02 | 72 | hr | 1476 | 925 | 3731 | 0.2479 | -0.2952 |
| SK-BR-3 | SNS-032 | 3.33 | uM | LJP6 | 2 | H14 | 72 | hr | 1476 | 920 | 3783 | 0.2432 | -0.2944 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP5 | 3 | C20 | 72 | hr | 929 | 494 | 3263 | 0.1514 | -0.2943 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP6 | 1 | C20 | 72 | hr | 929 | 501 | 3185 | 0.1573 | -0.2936 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 3 | A17 | 72 | hr | 1235 | 675 | 4126 | 0.1636 | -0.2935 |
| MCF7 | SNS-032 | 0.37 | uM | LJP6 | 2 | H16 | 72 | hr | 1235 | 680 | 4070 | 0.1671 | -0.2933 |
| BT-20 | AZD7762 | 10 | uM | LJP6 | 3 | L01 | 72 | hr | 1657 | 906 | 5546 | 0.1634 | -0.2930 |
| MCF7 | GSK1059615 | 10 | uM | LJP6 | 1 | C01 | 72 | hr | 1235 | 689 | 3974 | 0.1734 | -0.2928 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 3 | G01 | 72 | hr | 513 | 114 | 10483 | 0.0109 | -0.2923 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 2 | F03 | 72 | hr | 1235 | 659 | 4356 | 0.1513 | -0.2922 |
| SK-BR-3 | Nintedanib | 10 | uM | LJP6 | 3 | H01 | 72 | hr | 1476 | 930 | 3734 | 0.2491 | -0.2921 |
| BT-20 | CGP60474 | 3.33 | uM | LJP6 | 3 | G02 | 72 | hr | 1657 | 908 | 5546 | 0.1637 | -0.2921 |
| SK-BR-3 | SNS-032 | 0.12 | uM | LJP6 | 1 | H17 | 72 | hr | 1476 | 974 | 3413 | 0.2854 | -0.2913 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 1476 | 974 | 3413 | 0.2854 | -0.2913 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 1 | D22 | 72 | hr | 1476 | 926 | 3788 | 0.2444 | -0.2906 |
| BT-20 | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 1657 | 938 | 5244 | 0.1788 | -0.2902 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 1 | F01 | 72 | hr | 1235 | 681 | 4119 | 0.1653 | -0.2902 |
| BT-20 | Withaferin A | 10 | uM | LJP5 | 2 | G13 | 72 | hr | 1657 | 908 | 5610 | 0.1618 | -0.2898 |
| BT-20 | Buparlisib | 10 | uM | LJP5 | 1 | H01 | 72 | hr | 1657 | 908 | 5624 | 0.1614 | -0.2893 |
| BT-20 | GSK1059615 | 10 | uM | LJP6 | 3 | C01 | 72 | hr | 1657 | 918 | 5546 | 0.1655 | -0.2877 |
| SK-BR-3 | Dasatinib | 10 | uM | LJP6 | 2 | I01 | 72 | hr | 1476 | 933 | 3783 | 0.2466 | -0.2870 |
| MCF7 | PF562271 | 10 | uM | LJP6 | 3 | F13 | 72 | hr | 1235 | 686 | 4126 | 0.1663 | -0.2869 |
| MDA-MB-231 | Celastrol | 10 | uM | LJP6 | 1 | G07 | 72 | hr | 868 | 446 | 3429 | 0.1300 | -0.2854 |