LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 CP724714
10
uM
LJP5
 3
A07
 72
hr
 1235 2135 4326 0.4935 0.3533
MCF7 BX-912
1.11
uM
LJP5
 3
L21
 72
hr
 1235 2443 4326 0.5647 0.4580
MCF7 BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 1235 1858 4356 0.4265 0.2517
MCF7 BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 1235 1963 4326 0.4537 0.2919
MCF7 Dasatinib
0.04
uM
LJP5
 1
D06
 72
hr
 1235 2903 4119 0.7048 0.6352
MCF7 Dasatinib
0.04
uM
LJP5
 2
D06
 72
hr
 1235 2660 4356 0.6106 0.5248
MCF7 Dasatinib
0.04
uM
LJP5
 3
D06
 72
hr
 1235 2301 4326 0.5319 0.4105
MCF7 Dasatinib
1.11
uM
LJP5
 3
D03
 72
hr
 1235 1076 4326 0.2487 -0.0735
MCF7 Seliciclib
0.04
uM
LJP5
 2
J06
 72
hr
 1235 4880 4356 1.1202 1.1289
MCF7 Dasatinib
3.33
uM
LJP5
 3
D02
 72
hr
 1235 923 4326 0.2133 -0.1489
MCF7 Dasatinib
0.12
uM
LJP5
 1
D05
 72
hr
 1235 1295 4119 0.3144 0.0275
MCF7 Dasatinib
0.12
uM
LJP5
 2
D05
 72
hr
 1235 1226 4356 0.2814 -0.0042
MCF7 Dasatinib
0.12
uM
LJP5
 3
D05
 72
hr
 1235 1300 4326 0.3005 0.0286
MCF7 Seliciclib
0.37
uM
LJP5
 2
J04
 72
hr
 1235 3684 4356 0.8457 0.8239
MCF7 Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 1235 1361 4326 0.3146 0.0550
MCF7 Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 1235 1405 4119 0.3411 0.0769
MCF7 Dasatinib
0.37
uM
LJP5
 1
D04
 72
hr
 1235 931 4119 0.2260 -0.1503
MCF7 Dasatinib
0.37
uM
LJP5
 2
D04
 72
hr
 1235 913 4356 0.2096 -0.1532
MCF7 Dasatinib
0.37
uM
LJP5
 3
D04
 72
hr
 1235 876 4326 0.2025 -0.1731
MCF7 Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 1235 1502 4356 0.3448 0.1135
MCF7 Seliciclib
10
uM
LJP5
 2
J01
 72
hr
 1235 687 4356 0.1577 -0.2759
MCF7 Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 1235 1519 4119 0.3688 0.1263
MCF7 Dasatinib
1.11
uM
LJP5
 1
D03
 72
hr
 1235 1004 4119 0.2437 -0.1125
MCF7 AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 1235 4063 4356 0.9327 0.9248
MCF7 AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 1235 3646 4119 0.8851 0.8643