LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 AZD8055
1.11
uM
LJP6
 2
A09
 72
hr
 1235 1227 4070 0.3015 -0.0040
MCF7 AZD8055
1.11
uM
LJP6
 1
A09
 72
hr
 1235 1397 3974 0.3515 0.0757
MCF7 AZD8055
0.37
uM
LJP6
 3
A10
 72
hr
 1235 1235 4126 0.2993 -0.0002
SK-BR-3 AZD8055
0.37
uM
LJP6
 3
A10
 72
hr
 1476 1479 3734 0.3961 0.0012
MDA-MB-231 AZD8055
0.37
uM
LJP6
 1
A10
 72
hr
 868 1627 3429 0.4744 0.3729
MCF7 AZD8055
0.37
uM
LJP6
 2
A10
 72
hr
 1235 1236 4070 0.3037 0.0003
MCF7 AZD8055
0.37
uM
LJP6
 1
A10
 72
hr
 1235 1396 3974 0.3513 0.0752
BT-20 CP724714
0.37
uM
LJP5
 1
A10
 72
hr
 1657 5057 5624 0.8992 0.8829
MDA-MB-231 AZD8055
0.37
uM
LJP6
 2
A10
 72
hr
 868 1357 3652 0.3716 0.2405
SK-BR-3 CP724714
0.37
uM
LJP5
 1
A10
 72
hr
 1476 1912 3788 0.5047 0.2093
Hs 578T AZD8055
0.37
uM
LJP6
 3
A10
 72
hr
 929 1267 3243 0.3906 0.1876
MCF7 CP724714
0.37
uM
LJP5
 3
A10
 72
hr
 1235 3494 4326 0.8076 0.7771
Hs 578T AZD8055
0.37
uM
LJP6
 1
A10
 72
hr
 929 1235 3185 0.3877 0.1736
MCF7 CP724714
0.37
uM
LJP5
 2
A10
 72
hr
 1235 3323 4356 0.7628 0.7233
Hs 578T AZD8055
0.37
uM
LJP6
 2
A10
 72
hr
 929 1328 3221 0.4122 0.2203
MCF7 CP724714
0.37
uM
LJP5
 1
A10
 72
hr
 1235 3413 4119 0.8286 0.7948
SK-BR-3 CP724714
0.37
uM
LJP5
 2
A10
 72
hr
 1476 1877 3731 0.5031 0.1965
SK-BR-3 CP724714
0.37
uM
LJP5
 3
A10
 72
hr
 1476 1604 3796 0.4225 0.0626
MDA-MB-231 AZD8055
0.37
uM
LJP6
 3
A10
 72
hr
 868 1111 3587 0.3097 0.1281
Hs 578T CP724714
0.37
uM
LJP5
 3
A10
 72
hr
 929 3208 3263 0.9829 0.9811
MDA-MB-231 CP724714
0.37
uM
LJP5
 2
A10
 72
hr
 868 2567 3505 0.7323 0.7133
SK-BR-3 AZD8055
0.37
uM
LJP6
 2
A10
 72
hr
 1476 1503 3783 0.3973 0.0131
MDA-MB-231 CP724714
0.37
uM
LJP5
 3
A10
 72
hr
 868 2816 3440 0.8185 0.8082
SK-BR-3 AZD8055
0.37
uM
LJP6
 1
A10
 72
hr
 1476 1441 3413 0.4222 -0.0201
Hs 578T CP724714
0.37
uM
LJP5
 1
A10
 72
hr
 929 2960 3194 0.9266 0.9162