LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Mitoxantrone
0.12
uM
LJP6
 3
C23
 72
hr
 513 785 10494 0.0748 0.1025
MCF 10A Mitoxantrone
0.12
uM
LJP5
 1
C23
 72
hr
 513 430 10254 0.0419 -0.0402
MCF 10A Mitoxantrone
0.12
uM
LJP5
 2
C23
 72
hr
 513 848 10349 0.0819 0.1228
MCF 10A Mitoxantrone
0.12
uM
LJP5
 3
C23
 72
hr
 513 710 10483 0.0677 0.0774
MCF 10A Mitoxantrone
0.37
uM
LJP6
 1
C22
 72
hr
 513 510 10537 0.0484 -0.0015
MCF 10A Mitoxantrone
0.37
uM
LJP6
 2
C22
 72
hr
 513 539 10386 0.0519 0.0113
MCF 10A Mitoxantrone
0.37
uM
LJP6
 3
C22
 72
hr
 513 608 10494 0.0579 0.0396
MCF 10A Mitoxantrone
0.37
uM
LJP5
 1
C22
 72
hr
 513 467 10254 0.0455 -0.0217
MCF 10A Mitoxantrone
0.37
uM
LJP5
 2
C22
 72
hr
 513 544 10349 0.0526 0.0135
MCF 10A Mitoxantrone
0.37
uM
LJP5
 3
C22
 72
hr
 513 656 10483 0.0626 0.0580
MCF 10A Mitoxantrone
1.11
uM
LJP6
 1
C21
 72
hr
 513 456 10537 0.0433 -0.0268
MCF 10A Mitoxantrone
1.11
uM
LJP6
 2
C21
 72
hr
 513 520 10386 0.0501 0.0030
MCF 10A Mitoxantrone
1.11
uM
LJP6
 3
C21
 72
hr
 513 399 10494 0.0380 -0.0562
MCF 10A Mitoxantrone
1.11
uM
LJP5
 1
C21
 72
hr
 513 362 10254 0.0353 -0.0777
MCF 10A Mitoxantrone
1.11
uM
LJP5
 2
C21
 72
hr
 513 401 10349 0.0387 -0.0554
MCF 10A Mitoxantrone
1.11
uM
LJP5
 3
C21
 72
hr
 513 398 10483 0.0380 -0.0568
MCF 10A Mitoxantrone
3.33
uM
LJP6
 1
C20
 72
hr
 513 355 10537 0.0337 -0.0811
MCF 10A Mitoxantrone
3.33
uM
LJP6
 2
C20
 72
hr
 513 462 10386 0.0445 -0.0240
MCF 10A Mitoxantrone
3.33
uM
LJP6
 3
C20
 72
hr
 513 404 10494 0.0385 -0.0535
MCF 10A Mitoxantrone
3.33
uM
LJP5
 1
C20
 72
hr
 513 365 10254 0.0356 -0.0759
MCF 10A Mitoxantrone
3.33
uM
LJP5
 2
C20
 72
hr
 513 382 10349 0.0369 -0.0659
MCF 10A Mitoxantrone
3.33
uM
LJP5
 3
C20
 72
hr
 513 366 10483 0.0349 -0.0748
MCF 10A Mitoxantrone
10
uM
LJP6
 1
C19
 72
hr
 513 449 10537 0.0426 -0.0303
MCF 10A Mitoxantrone
10
uM
LJP6
 2
C19
 72
hr
 513 451 10386 0.0434 -0.0294
MCF 10A Mitoxantrone
10
uM
LJP6
 3
C19
 72
hr
 513 492 10494 0.0469 -0.0097