LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 3 | L02 | 72 | hr | 1235 | 1060 | 4126 | 0.2569 | -0.0842 |
| MCF7 | AZD7762 | 10 | uM | LJP6 | 1 | L01 | 72 | hr | 1235 | 728 | 3974 | 0.1832 | -0.2693 |
| MCF7 | AZD7762 | 10 | uM | LJP6 | 2 | L01 | 72 | hr | 1235 | 796 | 4070 | 0.1956 | -0.2255 |
| MCF7 | AZD7762 | 10 | uM | LJP6 | 3 | L01 | 72 | hr | 1235 | 773 | 4126 | 0.1873 | -0.2362 |
| MCF7 | AZD8055 | 0.04 | uM | LJP6 | 1 | A12 | 72 | hr | 1235 | 1330 | 3974 | 0.3347 | 0.0448 |
| MCF7 | AZD8055 | 0.04 | uM | LJP6 | 2 | A12 | 72 | hr | 1235 | 1464 | 4070 | 0.3597 | 0.1037 |
| MCF7 | AZD8055 | 0.04 | uM | LJP6 | 3 | A12 | 72 | hr | 1235 | 1129 | 4126 | 0.2736 | -0.0504 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 1 | A11 | 72 | hr | 1235 | 1329 | 3974 | 0.3344 | 0.0443 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 2 | A11 | 72 | hr | 1235 | 1279 | 4070 | 0.3142 | 0.0204 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 3 | A11 | 72 | hr | 1235 | 1350 | 4126 | 0.3272 | 0.0523 |
| MCF7 | AZD8055 | 0.37 | uM | LJP6 | 1 | A10 | 72 | hr | 1235 | 1396 | 3974 | 0.3513 | 0.0752 |
| MCF7 | AZD8055 | 0.37 | uM | LJP6 | 2 | A10 | 72 | hr | 1235 | 1236 | 4070 | 0.3037 | 0.0003 |
| MCF7 | AZD8055 | 0.37 | uM | LJP6 | 3 | A10 | 72 | hr | 1235 | 1235 | 4126 | 0.2993 | -0.0002 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 1 | A09 | 72 | hr | 1235 | 1397 | 3974 | 0.3515 | 0.0757 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 2 | A09 | 72 | hr | 1235 | 1227 | 4070 | 0.3015 | -0.0040 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 3 | A09 | 72 | hr | 1235 | 1251 | 4126 | 0.3032 | 0.0072 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 1 | A08 | 72 | hr | 1235 | 1388 | 3974 | 0.3493 | 0.0715 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 2 | A08 | 72 | hr | 1235 | 1154 | 4070 | 0.2835 | -0.0388 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 3 | A08 | 72 | hr | 1235 | 1184 | 4126 | 0.2869 | -0.0241 |
| MCF7 | AZD8055 | 10 | uM | LJP6 | 1 | A07 | 72 | hr | 1235 | 1197 | 3974 | 0.3012 | -0.0186 |
| MCF7 | AZD8055 | 10 | uM | LJP6 | 2 | A07 | 72 | hr | 1235 | 1120 | 4070 | 0.2752 | -0.0554 |
| MCF7 | AZD8055 | 10 | uM | LJP6 | 3 | A07 | 72 | hr | 1235 | 1032 | 4126 | 0.2501 | -0.0982 |
| MCF7 | Sorafenib | 0.04 | uM | LJP6 | 1 | B12 | 72 | hr | 1235 | 4045 | 3974 | 1.0178 | 1.0211 |
| MCF7 | Sorafenib | 0.04 | uM | LJP6 | 2 | B12 | 72 | hr | 1235 | 3919 | 4070 | 0.9628 | 0.9564 |
| MCF7 | Sorafenib | 0.04 | uM | LJP6 | 3 | B12 | 72 | hr | 1235 | 3858 | 4126 | 0.9350 | 0.9242 |