LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Pictilisib
0.37
uM
LJP6
 72
hr
 1097 1857 3769 0.4927 0.2844
BT-20 Gefitinib
0.37
uM
LJP6
 72
hr
 1097 3297 3769 0.8748 0.8234
BT-20 Geldanamycin
0.37
uM
LJP5
 72
hr
 1097 1091 3769 0.2895 -0.0022
BT-20 Geldanamycin
0.37
uM
LJP6
 72
hr
 1097 952 3769 0.2527 -0.0541
BT-20 GSK1059615
0.37
uM
LJP5
 72
hr
 1097 1427 3769 0.3787 0.1235
BT-20 GSK1059615
0.37
uM
LJP6
 72
hr
 1097 1796 3769 0.4766 0.2617
BT-20 GSK1904529A
0.37
uM
LJP6
 72
hr
 1097 3352 3769 0.8893 0.8439
BT-20 Omipalisib
0.37
uM
LJP6
 72
hr
 1097 608 3769 0.1615 -0.1828
BT-20 GSK 690693
0.37
uM
LJP5
 72
hr
 1097 2343 3769 0.6217 0.4663
BT-20 GW843682X
0.37
uM
LJP6
 72
hr
 1097 1471 3769 0.3904 0.1401
BT-20 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1097 3391 3769 0.8998 0.8586
BT-20 HG-5-88-01
0.37
uM
LJP6
 72
hr
 1097 3375 3769 0.8955 0.8526
BT-20 Imatinib
0.37
uM
LJP6
 72
hr
 1097 3668 3769 0.9732 0.9621
BT-20 JNK-9L
0.37
uM
LJP6
 72
hr
 1097 1983 3769 0.5261 0.3315
BT-20 JW-7-24-1
0.37
uM
LJP6
 72
hr
 1097 2874 3769 0.7626 0.6651
BT-20 Lapatinib
0.37
uM
LJP6
 72
hr
 1097 3373 3769 0.8950 0.8519
BT-20 LDN-193189
0.37
uM
LJP5
 72
hr
 1097 3201 3769 0.8493 0.7874
BT-20 Linifanib
0.37
uM
LJP6
 72
hr
 1097 3801 3769 1.0083 1.0118
BT-20 Linsitinib
0.37
uM
LJP5
 72
hr
 1097 3689 3769 0.9787 0.9700
BT-20 Mitoxantrone
0.37
uM
LJP5
 72
hr
 1097 917 3769 0.2433 -0.0675
BT-20 Mitoxantrone
0.37
uM
LJP6
 72
hr
 1097 994 3769 0.2638 -0.0385
BT-20 MK2206
0.37
uM
LJP6
 72
hr
 1097 2365 3769 0.6276 0.4747
BT-20 Neratinib
0.37
uM
LJP5
 72
hr
 1097 2260 3769 0.5997 0.4354
BT-20 Nilotinib
0.37
uM
LJP5
 72
hr
 1097 3882 3769 1.0300 1.0423
BT-20 Afatinib
0.04
uM
LJP6
 72
hr
 1097 2874 3769 0.7625 0.6650