LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
SK-BR-3 Afatinib
0.04
uM
LJP6
 72
hr
 1401 1437 4223 0.3404 0.0127
MCF7 Afatinib
1.11
uM
LJP6
 72
hr
 1209 2817 4093 0.6883 0.5575
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 658 3670 3846 0.9542 0.9448
BT-20 Afatinib
10.0
uM
LJP6
 72
hr
 1097 816 3769 0.2166 -0.1051
SK-BR-3 Afatinib
0.12
uM
LJP6
 72
hr
 1401 1416 4223 0.3354 0.0052
MDA-MB-231 Afatinib
10.0
uM
LJP6
 72
hr
 1235 628 4513 0.1393 -0.1853
Hs 578T Afatinib
10.0
uM
LJP6
 72
hr
 658 457 3846 0.1188 -0.0631
MCF 10A Afatinib
10.0
uM
LJP6
 72
hr
 962 1227 10605 0.1157 0.0275
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 658 3556 3846 0.9247 0.9092
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1097 3253 3769 0.8631 0.8068
MDA-MB-231 Afatinib
1.11
uM
LJP6
 72
hr
 1235 2739 4513 0.6069 0.4587
MCF7 Afatinib
0.37
uM
LJP6
 72
hr
 1209 3723 4093 0.9096 0.8717
MDA-MB-231 Afatinib
0.37
uM
LJP6
 72
hr
 1235 3577 4513 0.7926 0.7144
MCF 10A Afatinib
1.11
uM
LJP6
 72
hr
 962 1383 10605 0.1304 0.0436
MDA-MB-231 Afatinib
3.33
uM
LJP6
 72
hr
 1235 2749 4513 0.6090 0.4616
MCF7 Afatinib
3.33
uM
LJP6
 72
hr
 1209 3086 4093 0.7541 0.6510
MDA-MB-231 Afatinib
0.12
uM
LJP6
 72
hr
 1235 4078 4513 0.9036 0.8673
MCF 10A Afatinib
3.33
uM
LJP6
 72
hr
 962 1483 10605 0.1399 0.0541
BT-20 Afatinib
0.04
uM
LJP6
 72
hr
 1097 2874 3769 0.7625 0.6650
MCF 10A Afatinib
0.12
uM
LJP6
 72
hr
 962 1521 10605 0.1435 0.0580
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1209 3666 4093 0.8958 0.8520
SK-BR-3 Afatinib
0.37
uM
LJP6
 72
hr
 1401 1401 4223 0.3318 -0.0002
Hs 578T Alpelisib
10.0
uM
LJP5
 72
hr
 658 2213 3846 0.5755 0.4878
MCF7 Alpelisib
10.0
uM
LJP5
 72
hr
 1209 1130 4093 0.2762 -0.0275
BT-20 Alpelisib
1.11
uM
LJP5
 72
hr
 1097 2083 3769 0.5527 0.3690