LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
SK-BR-3 Brivanib
1.11
uM
LJP5
 72
hr
 1401 4209 4223 0.9967 0.9951
SK-BR-3 Brivanib
3.33
uM
LJP5
 72
hr
 1401 4138 4223 0.9799 0.9698
SK-BR-3 Brivanib
0.37
uM
LJP5
 72
hr
 1401 4205 4223 0.9957 0.9936
BT-20 Brivanib
0.37
uM
LJP5
 72
hr
 1097 3699 3769 0.9813 0.9736
MCF 10A Buparlisib
0.04
uM
LJP5
 72
hr
 962 10708 10605 1.0097 1.0107
MCF7 Buparlisib
0.04
uM
LJP5
 72
hr
 1209 2423 4093 0.5922 0.4211
MCF7 Buparlisib
10.0
uM
LJP5
 72
hr
 1209 854 4093 0.2087 -0.1232
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 72
hr
 1235 1350 4513 0.2992 0.0349
BT-20 Buparlisib
3.33
uM
LJP5
 72
hr
 1097 732 3769 0.1942 -0.1367
BT-20 Buparlisib
0.04
uM
LJP5
 72
hr
 1097 3777 3769 1.0021 1.0029
MCF 10A Buparlisib
0.37
uM
LJP5
 72
hr
 962 9430 10605 0.8893 0.8782
MDA-MB-231 Buparlisib
0.04
uM
LJP5
 72
hr
 1235 4633 4513 1.0265 1.0365
Hs 578T Buparlisib
10.0
uM
LJP5
 72
hr
 658 395 3846 0.1029 -0.0823
Hs 578T Buparlisib
0.37
uM
LJP5
 72
hr
 658 2458 3846 0.6392 0.5647
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 72
hr
 1235 4457 4513 0.9875 0.9828
Hs 578T Buparlisib
0.04
uM
LJP5
 72
hr
 658 3642 3846 0.9470 0.9361
Hs 578T Buparlisib
1.11
uM
LJP5
 72
hr
 658 1105 3846 0.2874 0.1403
MCF 10A Buparlisib
0.12
uM
LJP5
 72
hr
 962 10235 10605 0.9651 0.9616
SK-BR-3 Buparlisib
0.12
uM
LJP5
 72
hr
 1401 2767 4223 0.6553 0.4841
MCF7 Buparlisib
0.37
uM
LJP5
 72
hr
 1209 1418 4093 0.3465 0.0724
MCF7 Buparlisib
3.33
uM
LJP5
 72
hr
 1209 838 4093 0.2048 -0.1287
MCF7 Buparlisib
1.11
uM
LJP5
 72
hr
 1209 977 4093 0.2389 -0.0804
BT-20 Buparlisib
1.11
uM
LJP5
 72
hr
 1097 1147 3769 0.3044 0.0187
Hs 578T Buparlisib
3.33
uM
LJP5
 72
hr
 658 477 3846 0.1241 -0.0567
MCF 10A Buparlisib
3.33
uM
LJP5
 72
hr
 962 1383 10605 0.1304 0.0436