LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A A443654
0.12
uM
LJP6
 72
hr
 962 7796 10605 0.7352 0.7087
MCF7 A443654
3.33
uM
LJP6
 72
hr
 1209 636 4093 0.1554 -0.1989
MCF 10A A443654
0.04
uM
LJP6
 72
hr
 962 10928 10605 1.0305 1.0336
BT-20 A443654
0.37
uM
LJP6
 72
hr
 1097 728 3769 0.1933 -0.1379
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 962 1706 10605 0.1609 0.0772
Hs 578T A443654
0.37
uM
LJP6
 72
hr
 658 384 3846 0.0998 -0.0860
BT-20 A443654
3.33
uM
LJP6
 72
hr
 1097 469 3769 0.1246 -0.2349
BT-20 A443654
10.0
uM
LJP6
 72
hr
 1097 437 3769 0.1161 -0.2468
Hs 578T A443654
0.04
uM
LJP6
 72
hr
 658 2140 3846 0.5566 0.4650
Hs 578T A443654
0.12
uM
LJP6
 72
hr
 658 940 3846 0.2446 0.0886
MCF 10A A443654
3.33
uM
LJP6
 72
hr
 962 316 10605 0.0298 -0.0670
MCF 10A Afatinib
0.37
uM
LJP6
 72
hr
 962 1405 10605 0.1325 0.0460
MCF 10A Afatinib
1.11
uM
LJP6
 72
hr
 962 1383 10605 0.1304 0.0436
Hs 578T Afatinib
1.11
uM
LJP6
 72
hr
 658 3341 3846 0.8687 0.8416
Hs 578T Afatinib
10.0
uM
LJP6
 72
hr
 658 457 3846 0.1188 -0.0631
MCF7 Afatinib
10.0
uM
LJP6
 72
hr
 1209 922 4093 0.2254 -0.0995
MDA-MB-231 Afatinib
0.04
uM
LJP6
 72
hr
 1235 4254 4513 0.9426 0.9209
MCF7 Afatinib
1.11
uM
LJP6
 72
hr
 1209 2817 4093 0.6883 0.5575
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 658 3556 3846 0.9247 0.9092
MCF7 Afatinib
3.33
uM
LJP6
 72
hr
 1209 3086 4093 0.7541 0.6510
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 658 3670 3846 0.9542 0.9448
Hs 578T Afatinib
3.33
uM
LJP6
 72
hr
 658 3389 3846 0.8812 0.8567
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1097 3253 3769 0.8631 0.8068
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1209 3665 4093 0.8955 0.8517
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1209 3666 4093 0.8958 0.8520