LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 AZD-6482
10.0
uM
LJP5
 72
hr
 1097 792 3769 0.2103 -0.1140
BT-20 AZD-6482
0.04
uM
LJP5
 72
hr
 1097 3658 3769 0.9704 0.9583
SK-BR-3 AZD-6482
3.33
uM
LJP5
 72
hr
 1401 2731 4223 0.6468 0.4713
MCF 10A AZD-6482
0.12
uM
LJP5
 72
hr
 962 10337 10605 0.9747 0.9722
SK-BR-3 AZD-6482
1.11
uM
LJP5
 72
hr
 1401 3566 4223 0.8445 0.7672
BT-20 AZD-6482
3.33
uM
LJP5
 72
hr
 1097 1442 3769 0.3827 0.1293
Hs 578T AZD-6482
0.12
uM
LJP5
 72
hr
 658 3513 3846 0.9136 0.8957
Hs 578T AZD-6482
0.37
uM
LJP5
 72
hr
 658 3419 3846 0.8890 0.8661
MDA-MB-231 AZD-6482
10.0
uM
LJP5
 72
hr
 1235 3063 4513 0.6787 0.5575
MCF 10A AZD-6482
0.04
uM
LJP5
 72
hr
 962 10549 10605 0.9947 0.9942
MCF 10A AZD-6482
1.11
uM
LJP5
 72
hr
 962 10023 10605 0.9452 0.9397
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 72
hr
 1235 4318 4513 0.9567 0.9403
MCF7 AZD-6482
3.33
uM
LJP5
 72
hr
 1209 3144 4093 0.7683 0.6711
Hs 578T AZD-6482
10.0
uM
LJP5
 72
hr
 658 1861 3846 0.4840 0.3775
Hs 578T AZD-6482
1.11
uM
LJP5
 72
hr
 658 3043 3846 0.7913 0.7482
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 72
hr
 1235 3974 4513 0.8806 0.8356
MCF 10A AZD-6482
0.37
uM
LJP5
 72
hr
 962 10138 10605 0.9560 0.9516
BT-20 AZD-6482
1.11
uM
LJP5
 72
hr
 1097 2110 3769 0.5599 0.3792
MCF7 AZD-6482
1.11
uM
LJP5
 72
hr
 1209 3734 4093 0.9125 0.8757
MCF7 AZD-6482
0.04
uM
LJP5
 72
hr
 1209 4152 4093 1.0146 1.0207
MCF7 AZD-6482
10.0
uM
LJP5
 72
hr
 1209 1478 4093 0.3613 0.0933
MCF7 AZD-6482
0.12
uM
LJP5
 72
hr
 1209 4042 4093 0.9877 0.9825
Hs 578T AZD-6482
0.04
uM
LJP5
 72
hr
 658 3702 3846 0.9627 0.9550
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 72
hr
 1235 3381 4513 0.7491 0.6544
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 72
hr
 1235 3777 4513 0.8369 0.7754