LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A GSK1904529A
0.04
uM
LJP6
 72
hr
 962 9104 10605 0.8585 0.8444
MDA-MB-231 R406
0.04
uM
LJP6
 72
hr
 1235 4461 4513 0.9884 0.9840
BT-20 LDN-193189
0.04
uM
LJP5
 72
hr
 1097 3807 3769 1.0099 1.0140
MCF 10A GW843682X
0.04
uM
LJP6
 72
hr
 962 9967 10605 0.9399 0.9339
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 72
hr
 1235 1876 4513 0.4157 0.1954
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 72
hr
 1235 4766 4513 1.0559 1.0770
MCF 10A HG-5-88-01
0.04
uM
LJP6
 72
hr
 962 10682 10605 1.0073 1.0080
MDA-MB-231 Omipalisib
0.04
uM
LJP6
 72
hr
 1235 2003 4513 0.4438 0.2341
MCF 10A HG-5-113-01
0.04
uM
LJP5
 72
hr
 962 10133 10605 0.9555 0.9510
MDA-MB-231 GW843682X
0.04
uM
LJP6
 72
hr
 1235 4047 4513 0.8968 0.8578
BT-20 Linifanib
0.04
uM
LJP6
 72
hr
 1097 3950 3769 1.0481 1.0678
BT-20 Sigma A6730
0.04
uM
LJP5
 72
hr
 1097 3200 3769 0.8491 0.7871
BT-20 SB590885
0.04
uM
LJP5
 72
hr
 1097 3918 3769 1.0395 1.0557
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 658 605 3846 0.1575 -0.0165
BT-20 Celastrol
0.04
uM
LJP6
 72
hr
 1097 3972 3769 1.0539 1.0760
Hs 578T Mitoxantrone
0.04
uM
LJP5
 72
hr
 658 707 3846 0.1838 0.0153
Hs 578T PD0325901
0.04
uM
LJP6
 72
hr
 658 2223 3846 0.5782 0.4911
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 658 3634 3846 0.9450 0.9337
BT-20 Linsitinib
0.04
uM
LJP5
 72
hr
 1097 3436 3769 0.9116 0.8753
Hs 578T Nilotinib
0.04
uM
LJP5
 72
hr
 658 4075 3846 1.0597 1.0720
BT-20 AT-7519
0.04
uM
LJP6
 72
hr
 1097 3026 3769 0.8028 0.7218
Hs 578T MK2206
0.04
uM
LJP6
 72
hr
 658 3276 3846 0.8519 0.8213
BT-20 AZD8055
0.04
uM
LJP6
 72
hr
 1097 1423 3769 0.3775 0.1219
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 72
hr
 1235 3774 4513 0.8362 0.7744
MDA-MB-231 Linifanib
0.04
uM
LJP6
 72
hr
 1235 4674 4513 1.0356 1.0490