LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4570 | 4223 | 1.0823 | 1.1232 |
| SK-BR-3 | NVP-AEW541 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3835 | 4223 | 0.9081 | 0.8625 |
| SK-BR-3 | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1419 | 4223 | 0.3361 | 0.0063 |
| SK-BR-3 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1120 | 4223 | 0.2653 | -0.0997 |
| SK-BR-3 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2205 | 4223 | 0.5221 | 0.2848 |
| SK-BR-3 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1282 | 4223 | 0.3037 | -0.0421 |
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1375 | 4223 | 0.3258 | -0.0092 |
| SK-BR-3 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3680 | 4223 | 0.8714 | 0.8075 |
| SK-BR-3 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1289 | 4223 | 0.3052 | -0.0399 |
| SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1020 | 4223 | 0.2415 | -0.1352 |
| SK-BR-3 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 2731 | 4223 | 0.6468 | 0.4713 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1046 | 4223 | 0.2477 | -0.1260 |
| SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 711 | 4223 | 0.1684 | -0.2447 |
| SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 903 | 4223 | 0.2140 | -0.1765 |
| SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3054 | 4223 | 0.7233 | 0.5858 |